Duties: You will provide leadership to statistical staff on the indications/projects so that all work is carried out with regards to AZ standards and external regulations; through partnership with experts, developing design options and providing high quality decision support to enable the business to make informed decisions; quantifying the benefit, risk, value and uncertainty of the emerging product profile
Requirements: MSc or PhD degree in Statistics, Biostatistics, or related quantitative fields, or equivalent course work/technical experience; Understanding of regulations/developments in the area of Clinical Development and Biostatistics; Appropriate experience as a statistician for the relevant position level with clinical trials, pharmaceutical development, regulated research, and/or related areas of statistical applications; A collaborative mindset; A general dedication to and ability to apply expertise to problem solving

Duties: Lead strategic, statistical thinking and contributions to clinical development plans; Through collaboration with experts, develop design options and provide quantitative decision support; Innovate and improve study design through adaptive design and Bayesian methods, including trial simulation; Improve statistical methodology, processes and delivery activities; Oversee internal and external statisticians in the delivery of analysis and reporting; Interpret and present clinical trial results
Requirements: A Statistics, Mathematics, Biostatistics, related MS Degree; 5 years of proven experience; Direct experience of clinical trials, ideally in pharmaceuticals or healthcare; Excellent interpersonal skills

Duties: You will be working in the Oncology Biometrics Programming department providing statistical programming support related to the analysis and reporting process at project/study level for the delivery of the statistical programming aspects of clinical development. The scope of work includes, but is not limited to, clinical study report development, regulatory submissions, commercialization, and the scientific utilization of our data for AstraZeneca products. There are many career options that you can pursue for your development and progression
Requirements: Bachelor’s or Master’s (or local equivalent) degree in Mathematics, Statistics, Computer Science, Life or Social Sciences or related field; Ability to pay attention to detail and lead/work on concurrent studies and activities; Excellent verbal and written communication skills and ability to influence team members; Extensive SAS programming expertise to a high level within clinical drug development; Ability to work independently on the assigned programming tasks

Duties: Leading and managing team of internal and external biostatistics and statistical programming resources supporting studies and programs for identified therapeutic area(s) or phase(s) of development.Managing assignments and priorities of team members; Ensuring accurate, statistically valid deliverables included in protocols, statistical analysis plans, study reports, manuscripts, and regulatory submission documents; Coordinating achievement of major statistical deliverables and milestones in collaboration with other functions; Leveraging standardization to maximize global data integration and interpretability; Providing statistical leadership and support for feasibility assessments, clinical development plans, complex study designs, regulatory meetings, submissions and follow up; Providing statistical leadership for preparation of marketing applications (NDA/BLA) to FDA, EMA, or other worldwide regulatory agencies
Requirements: A PhD in Statistics/Biostatistics and at least 7 years of relevant pharmaceutical experience or a MSc in Statistics/Biostatistics and at least 10 years of relevant pharmaceutical experience; Comprehensive knowledge of statistical methodology in design and analysis of clinical trials including Bayesian modeling and adaptive design; regulatory requirements relating to clinical development of drugs and biologics; BLA/NDA experience including eCTD submissions; Working knowledge of major statistical software programs including SAS; Knowledge of CDISC requirements for SDTM and ADaM

Duties: In this role you will be responsible in leading the strategic, statistical thinking and contributions to the Development Plans, Regulatory Strategy, Health Technology Assessment and Commercial Presentation for indications/projects within an AZ product team. You will provide leadership to statistical staff on the indications/projects so that all work is carried out with regards to AZ standards and external regulations; through partnership with experts, developing design options and providing high quality decision support to enable the business to make informed decisions; quantifying the benefit, risk, value and uncertainty of the emerging product profile
Requirements: MSc or PhD degree in Statistics, Biostatistics, or related quantitative fields, or equivalent course work/technical experience; Understanding of regulations/developments in the area of Clinical Development and Biostatistics; Appropriate experience as a statistician for the relevant position level with clinical trials, pharmaceutical development, regulated research, and/or related areas of statistical applications

Duties: Collaborates with Clinical Development, Clinical Pharmacology, Regulatory and Clinical Operations expertise areas to design clinical trials; Writes the statistical sections of clinical trial protocols, while consulting with internal and external experts; Contributes to or prepares statistical analysis plans and Data Presentation Plans; Collaborates with Data Management, Clinical Development, Clinical Pharmacology and Clinical Operations on design of eCRFs; Provides statistical guidance on conduct of ongoing trials; Collaborates with Statistical Programmers on summary and analysis of trial data. Writes and/or reviews ADS and ad hoc analysis specifications
Requirements: PhD in Biostatistics, Statistics, or equivalent with at least 4 years pharmaceutical biostatistics experience or MS with at least 6 years of relevant experience; Excellent written and oral communication skills; Excellent presentation and interpersonal skills; Experience programming in SAS; Experience with simulations (design, implementation and interpretation); Understanding of ICH GCP as well as general knowledge of industry practices and standards; Familiarity with R programming language and other statistical software, including EAST

Duties: Responsible for the timely delivery of robust and visible demand forecasts for strategic brands/therapy areas and key markets, including clear documentation of assumptions as well as levels of confidence/robustness; Authoritatively/confidently present and defend forecast approach, methodology, assumptions and output to senior leadership; Ensure objectivity and robustness around the forecast via identification of the right data sources and application of industry-leading modeling approaches, with sensitivity analyses around key variables to assist in opportunity and risk management; Demonstrate a high level of understanding of the points of integration of our work and that of our colleagues; Develop new product introduction volume forecasts, both short-term and long-term, to foster into strategic and operational planning processes
Requirements: Bachelor’s Degree in relevant field; 6+ years of direct Pharmaceutical forecasting experience with an in-depth knowledge of forecasting techniques, models and approaches; Good understanding of one or more disease areas and how patients move through their respective diagnosis and treatment pathways, including treatment dynamics; Experience integrating insights from market research and secondary data analysis into forecast assumptions

Duties: Take a leadership role and drive statistical thinking in cross-functional team projects, within an international environment; Authoring statistical sections of important clinical document, SAP, CRS, Protocols etc and reviewing other sections from a statistical perspective; Contribute to Analysis and Reporting activities of internal delivered studies, including interim analyses; Lead the delivery and oversight on drug project(s) and/or studies to time, quality, and standards, including partnering with CROs and with Statistical Programming; Contribute to development of new procedures and standards to increase quality, efficiency, and effectiveness
Requirements: MSc/PhD in Statistics or Mathematics (containing a substantial statistical component) with experience in pharma/healthcare or other relevant area; Knowledge of the technical and regulatory requirements related to the role; Leadership capabilities to be able to lead and direct study and project work; Experience of data analysis and interpretation in a relevant area; Proficient in use of SAS including experience with development of reusable code

Duties: You will be working in the Oncology Biometrics Programming department reporting to a Sr. Director, Statistical Programming, providing leadership and management of standards governance activities at the therapeutic and study level related to the planning, execution and delivery of the data and the analysis reporting of clinical development. The scope of work includes, but is not limited to, the governance of clinical data standards change requests, development of new Oncology TA standards, and participation in cross-TA standards development activities
Requirements: Bachelor’s or Master’s (or local equivalent) degree in Mathematics, Statistics, Computer Science, Life or Social Sciences or related field; Support the Oncology Therapeutic Area Standards Definition Team by reviewing change requests from oncology study teams for standard components (with focus on SDTM, ADaM, TLF) to ensure compliance with the AZ & CDISC standards, regulatory guidelines and AZ Clinical data standards SOP, Protocol/SAP; Support study teams with questions related to oncology standards (with focus on SDTM, ADaM, TLF); Participate in and contribute to working groups (including SME’s) during review and optimisation of existing Corporate and Oncology Standards

Duties: Lead strategic, statistical thinking and contributions to clinical development plans; Through collaboration with experts, develop design options and provide quantitative decision support; Innovate and improve study design through adaptive design and Bayesian methods, including trial simulation; Improve statistical methodology, processes and delivery activities; Oversee internal and external statisticians in the delivery of analysis and reporting; Interpret and present clinical trial results
Requirements: A Statistics, Mathematics, Biostatistics, related MS Degree; 5 years of proven experience; Direct experience of clinical trials, ideally in pharmaceuticals or healthcare; Excellent interpersonal skills; A collaborative mindset; Genuine dedication to drive innovation to advance statistical science; Oncology experience would be an advantage

Duties: As an Associate Director, you will apply advanced statistical and machine learning methods to analyze multi-modal data aiming to potential biomarker and MoA (mechanism of action) insights. You will drive the development of biomarker identification, validation and patient stratification strategies in collaboration with cross-functional teams. You will effectively communicate complex findings and recommendations to diverse stakeholders through compelling data visualizations, reports, and presentations. You will also work with our Research and Translational Medicine Leads to proactively influence the generation of data assets as part of a data generation strategy to evaluate novel hypothesis and drive target discovery
Requirements: PhD in Data Science, Statistics, Bioinformatics, Computer Science, or a related quantitative field, with more than three years of experience in Pharma/Biotech or large cancer center; Extensive expertise in statistical analysis, machine learning, and advanced data manipulation techniques; Proficiency in programming languages such as Python, R, or similar; Significant experience in cancer biomarker analysis of multi-modal data from oncology clinical trials; Deep knowledge of cancer genetics and key algorithmic & statistical methods applicable to cancer genomics

Duties: Undertake design and analysis of complex studies and provide statistical support, making contributions to clinical development plans. Utilize adaptive design and Bayesian methods, including trial simulation, to innovate and improve study design. Execute strategic, statistical thinking and guide the direction to improve the statistical methodology, processes, and delivery activities of study design. Responsible for analyzing, interpreting, summarizing, and presenting results of clinical trials. Develop design options and provide quantitative decision support and will oversee internal and external statisticians in the delivery of analysis and reporting on our clinical program designs
Requirements: Must possess a Master’s or foreign equivalent, in Statistics, Mathematics, or a related field, and five (5) years of experience in the job offered, as a Statistician, or in a related occupation. Must possess five (5) years of experience all of the following: Designing Phase III Oncology clinical trials including adaptive designs or through Bayesian methods; R, R-shiny and SAS programming; Conducting simulations; Performing biomarker analyses; Developing and submitting sNDA and NDA; Developing scientific publications of clinical oncology trials

Duties: The Associate Director, Statistical Programming provides leadership, line management and development to a team, offering programming expertise and mentoring. This includes providing statistical programming expertise to support the design and interpretation of clinical studies and development programmes, effective management of initiatives to improve quality and integrity of information interpretation, as well as promotion of best practice and standards to enhance the value and contribution of programming across Respiratory & Immunology(R&I)
Requirements: BSc or post graduate qualification (or local equivalent) in Mathematics, Statistics, Informatics, Computer Science, Life or Social Sciences; Experience of pharma and the life sciences, with a comprehensive understanding of the R&D drug development lifecycleExcellent interpersonal skills; Genuine commitment to drive innovation and improve efficiency; Extensive SAS programming knowledge

Duties: The role is based in our new ground-breaking Discovery Centre (DISC) located on the Cambridge Biomedical Campus. This newly purpose-built building brings together the company’s research and development activity in a pioneering strategic R&D centre and global corporate headquarters. The building has been designed with open architecture reflecting AstraZeneca’s approach to research. Open laboratories and glass walls will enable new ways of working across teams, whilst a central courtyard will put science on full display. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn't mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and...
Requirements: Ph. D in bioinformatics or a related field; with relevant working experience; Experience in Illumina workflows, raw data analysis and NGS data integration and interpretation; Ability to apply data analysis methods efficiently to large data sets; Experience with programming scientific applications; Ability to explore novel bioinformatic approaches to improve sensitivity and specificity of NGS based workflows

Duties: The Senior/Principal Programmer provide Statistical Programming support and/or lead all programming related activities of the analysis and reporting process including, but not limited to, CSR development, regulatory activities and the scientific utilization of our data for AstraZeneca products. There are many career options you can pursue for progression including technical pathways, management of global projects or line management
Requirements: To succeed in this role, you’ll be an experienced programmer with good knowledge of technical and regulatory requirements related to programming within the pharmaceutical or healthcare industry. You’ll enjoy multitasking, have an appetite for solving problems with a strong team focus who enjoys collaborating to achieve the best results. We have several opportunities across both Senior and Principal levels