Aufgaben: Réaliser des analyses biochimiques d’échantillons sanguins (ELISA, tests colorimétriques); Réaliser des analyses en biologie moléculaire sur des échantillons sanguins (extraction ADN et ARN, expression de gènes, méthylation); Préparer les cocktails d’éléments traces métalliques; Suivre les oiseaux en expérimentation; Analyser les données issues du suivi RFID des oiseaux; Analyses statistiques descriptives des données de suivi des oiseaux, des résultats des analyses biochimiques et de biologie moléculaire
Anforderungen: Connaissances et fort intérêt en écophysiologie évolutive et écotoxicologie; Avoir un Master en écotoxicologie et/ou écophysiologie (au début du contrat en août); Formation opérateur en expérimentation animale (au minimum); Manipulation d’oiseaux; Manipulation de pipettes, centrifugeuse et autres matériels de bases d’un laboratoire de biochimie; Rigueur et intérêt pour le travail de paillasse; Analyse statistique des données avec le logiciel R; Connaissances des règles d’hygiène et sécurité pour la manipulation d’éléments traces métalliques; Travailler en équipe; Anglais scientifique de niveau B2 selon le cadre européen commun de référence pour les langues

Aufgaben: Preparation methods for the preparation of nanostructured materials and knowledge of spectroscopic techniques to optimize the efficiency of absorbing and converting visible radiation
Anforderungen: Early stage researcher or 0-4 yrs (Post graduate)

Aufgaben: Your general tasks will consist of; Independent research of high international quality, including publication; Teaching, guidance and examination of Bachelor’s and Master's degree students, as well as possibly co-supervision of PhD students; Contribution to external research funding; Development of national and international networks and collaborations in research; Your specific tasks will consist of developing a research program on the regulation of nitrogen fixation in legumes
Anforderungen: Applicants should hold a PhD in plant genetics and have a documented and strong publication record in the field of nitrogen fixation

Aufgaben: L’ingénieur(e) d'étude mènera ses activités au sein du laboratoire Géosciences Rennes et de l'OSUR. Son activité principale sera de développer et optimiser les méthodes et les outils d'étude des processus de colonisation, croissance et communication de bactéries sous écoulement dans des bioréacteurs et dans des systèmes microfluidiques
Anforderungen: Nous recherchons un ou une canditat.e possédant une excellente maîtrise des méthodes d'étude des interactions entre micro-organismes et écoulement de fluide; en conditions contrôlées. Une expérience en microfluidique avec des micro-organismes est demandée. Le ou la candidat(e) devra avoir un diplôme de master ou équivalent en microfluidique, biophysique, ingénierie biologique, microbiologie ou mécanique des fluides

Aufgaben: Recent improvements in machine learning have dramatically improved the accessibility of de novo protein design. In this project, we seek to exploit these developments to interrogate the role and mechanisms of receptor signalling in neuronal plasticity. The center of Excellence for “Protein in Memory” seeks to understand the molecular basis for memory with an emphasis on protein mechanism. Recent developments in protein structure prediction (e.g. AlphaFold2) and protein de novo design (e.g. RFDiffusion) have opened new possibilities for probing such mechanisms. The project will seek to use existing algorithms to new biological problems and is thus not focused on development of computational methods. We wish to generate small protein binders against a range of important neuroscience targets and use these for mechanistic studies in cellular models
Anforderungen: The project will involve both experimental and computational work and the candidate is expected to be comfortable with both. The candidate is expected to have (or being close to finishing) a Ph.D. in molecular biology, biochemistry, biophysics, biology, biotechnology, nanoscience or similar, and a good track record of productivity. Experience with some, but not all, of the following topics is an advantage: Recombinant protein expression and purification, biochemical and biophysical protein characterization, protein structure prediction or computational protein design. Furthermore, we expect an interest in interdisciplinarity and good collaboration skills

Aufgaben: Provide day-to-day management of Chemical laboratories and teaching spaces, including workflow organisation of practical class support; Proactively engage with teaching and research activities, in collaboration with academic staff, by providing specialist knowledge, trialling of processes and training on how to work on equipment and processes relevant to chemistry based science disciplines; Ensure that laboratory equipment and analytical instrumentation is maintained and operated to a safe and high standard and carry out minor repairs to equipment and coordinate with stakeholders within Deakin or outside service engineers as necessary
Anforderungen: A Degree in Chemistry/Science (or related field) with subsequent relevant experience; or; Extensive experience and specialist knowledge (including large scale chemistry instrumentation knowledge) or broad knowledge in technical or administrative fields or, an equivalent combination of relevant experience and/or education/training; Experience working collaboratively and effectively with multiple internal and external stakeholders clients and/or students

Aufgaben: The position includes experimental work on the interaction between free radicals (ROS and RNI) produced by activated host cells and the intracellular effect of new antibiotics against Mycobacterium tuberculosis. Methods included are measurement of ROS and RNI via -omics methods, flow cytometry including single-cell analysis and experiments in human macrophages and in a lung tissue model. Genetic and epigenetic effects on M. tuberculosis are also a part of the project which includes bioinformatic analysis. The position will also include design and analysis of experimental data and writing of reports for publication in scientific journals
Anforderungen: We are searching for a PhD in bioinformatics, molecular biology or microbiology. Documented experience and interest in bioinformatics, preferably within bacteriology and infection experiments in inflammatory cells is a requirement for the position

Aufgaben: The post holder will be responsible for characterising repair factors through structural biology techniques, with a focus on cryo-electron microscopy. Ideal candidates should have expertise in molecular cloning, protein expression, purification, and structural methods, preferably in crystallography and electron microscopy. Knowledge of DNA modification enzymes and a background in DNA damage and repair fields are highly desirable
Anforderungen: You will be required to have research experience in molecular cloning, cell culturing, cryo-electron microscopy, X-ray crystallography, and protein/complex characterization. A strong record of publishing in reputable journals and contributing to grant proposals is essential. Your role will involve managing research projects, mentoring junior researchers, collaborating internally and externally, and organizing and prioritizing work independently. Excellent written and oral communication skills, including presenting at international symposia and to non-specialist audiences, are also crucial

Dauer: temporary
Aufgaben: The research activity will cover topics related to rational design via CADD (Computer Aided Drug Design), synthesis and optimisation of compounds with potential anticancer, antibacterial and antiviral activity, and evaluation of their pharmacological activity. The project will also manage “omics” analyses and the data resulting from these activities, including the development of potential pharmaceutical probes for personalised medicine. It will involve the use of predictive techniques and advanced property-structure relationship methods applied to the study of the toxicity and bio-metabolic fate of chemical compounds with applications in the environmental, nutraceutical and pharmaceutical fields
Anforderungen: PhD or equivalent; Chemistry

Aufgaben: The focus of the project is on the functionalization of nanowires with DNA and their subsequent immobilization within DNA nanostructures. These structures will undergo characterization through Atomic Force Microscopy and Transmission Electron Microscopy
Anforderungen: The candidate should have a PhD degree within the broad field of (bio)chemical sciences and have experimental experience in DNA nanotechnology

Aufgaben: The subject area for the position is synthetic organic chemistry/medicinal chemistry. The aim of the project is to synthesize compounds with antimicrobial activity that can decompose under light into fragments that do not have antimicrobial activity. The project is a continuation of earlier work based on compounds containing our ethanolamine chemistry. Method development and chemical analysis will also be a central part of the project to, among other things, map photochemical degradation products. The person that will be hired will be involved in teaching duties at the department
Anforderungen: Applicants must hold a Norwegian PhD or an equivalent degree within synthetic organic chemistry or medicinal chemistry. PhD-students may apply if defence of the PhD-thesis is completed by September 1. It is a condition of employment that the PhD has been awarded; Experience from the use of modern analytical instrumentation, including running and interpretation of NMR-spectra (including two-dimensional NMR-techniques) is a requirement; Experience from multi step synthesis is an advantage

Aufgaben: The Swedish forestry sector is facing demands for increased carbon storage in forests with changed management practices. There is also a growing need for forest raw materials for both existing and new industrial applications. Which techniques regarding biofuel production, carbon capture and storage, and increased forest production work best in combination to continue to ensure sustainable production and allow for increased climate benefits for the Swedish forestry sector? This question forms the basis for system analyses of the Swedish forestry sector, based on detailed models for new and existing techniques for biofuels, CO2 storage, and increased forest production
Anforderungen: Qualification requirements Anyone who has a doctorate related forest science, forest industrial production systems, or optimization, or who has a degree from another country that is equivalent to a doctorate concerning analysis of large systems qualifies for the position

Abteilung: Biological Sciences; Laboratory Animal Science
Aufgaben: La febbre neurogenica (FN) è un'ipertermia che non risponde a trattamenti antipiretici e che emerge in risposta a emorragia subaracnoidea. Questo progetto mira a descrivere i centri del sistema nervoso centrale coinvolti nella generazione della FN. Gli obiettivi del progetto verranno raggiunti implementando tecniche elettrofisiologiche con approcci biomolecolari e farmacologici per valutare il ruolo dei modulatori infiammatori nell'insorgenza della NF. Aumentare le nostre conoscenze su questo sistema consentirà la progettazione di un nuovo approccio farmacologico al trattamento della FN. Il richiedente sarà responsabile di: condurre la maggior parte degli esperimenti, completare gli obiettivi del progetto, analizzare i dati, scrivere i risultati per la pubblicazione e presentare i risultati all'incontro nazionale. Il candidato riceverà una formazione diretta dal PI, parteciperà a regolari riunioni di laboratorio e journal club e avrà accesso a tutti i servizi dipartimentali
Anforderungen: Early stage researcher or 0-4 yrs (Post graduate)

Aufgaben: In this project, we will analyse a replication cohort, to verify the associations identified in the original analysis. Relationships between biomarker levels and existing risk scores, and future CVD development will be investigated. Interesting biomarkers will be selected for functional investigation, using various in vitro cell based systems. Effects of biomarker proteins on cell viability, migration, angiogenesis, thrombosis development and inflammation processes, and others, will be studied
Anforderungen: Qualification with a candidate medicine, or a master’s degree in biological sciences is required. Prior experience with cell culture-based laboratory projects and related molecular biology techniques, such as Western blot, qPCR, ELISA etc. is required. Prior experience with cardiovasular research projects and endothelial cell culture is beneficial, as is previous work with the analysis of patient samples and use of proteomics techniques. The candidate must be flexible and keen to work as part of a larger team

Aufgaben: You will be engaged in both laboratory experiments and bioinformatics analyses of multi-omics datasets generated from host-parasite model systems and environmental samples. Major part of this position will focus on analysis of host-virus dynamics and identifying the functional basis of their interactions but also includes working on other types of parasitic interactions in the lake ecosystem. The research includes fieldwork for lake sampling and sample processing as well as experimental manipulations in the laboratory, cultivation of the host and isolation of parasites, alternative analytical methods, multi-omics analyses and scientific communication
Anforderungen: A PhD degree (or equivalent) with specialization in microbiology, microbial ecology, molecular biology, bioinformatics or related areas; Proficiency in English speaking and writing; An analytical mind set and a keen interest in aquatic microbial ecology and phage genome evolution; A strong track record of scholar publications; Expertise in multi-omics analysis of microbes; Experience with field work and processing water samples

Aufgaben: You will be responsible for undertaking advanced academic study to underpin lectures and class teaching as well as lecture, tutor, (conduct practical classes using laboratory or workshop equipment), and supervise undergraduate and postgraduate students. You will be tasked with managing independent research projects or specific areas of research within a broad programme, to include: developing research questions within a specific context; conducting original research; analysing qualitative and/or quantitative data from a variety of sources, and developing appropriate analytical protocols and techniques to support research. You will also be responsible for liaising with examiners and academic staff regarding student performance and the development of new modules, and with funding bodies, stakeholders, and researchers in related fields to share information and expertise
Anforderungen: To be successful in this role, you will hold a relevant DPhil degree in a topic related to global health modelling, together with post-qualification experience. You will have expertise in infectious disease modelling and analytical techniques and demonstrate an interest in modelling for global health, and you will have experience with developing and delivering teaching as well as sufficient depth and breadth of knowledge in infectious disease modelling to develop course units

Abteilung: Medical Sciences; Medicine
Aufgaben: Pulmonary homografts is commonly used for RVOT reconstruction in congenital heart surgery. These conduits demonstrate reasonable outcomes in terms of hemodynamics, low thromboembolic risk and a better resistance to infection. However, there are some limiting factors associated with the use of homografts: availability, variability of duration and the inflammatory response. Several studies demonstrated the association between the characteristics of the donor, the method of preservation of the homograft, inflammatory response patient related and the degeneration of the conduit. Specifically, there is a consistent association between blood group and HLA-DR mismatch, short antibiotic preservation time and homograft valve failure; The impact of the inflammatory response on the surgical outcome after implantation of a pulmonary homograft represents an interesting topic of study to better understand the factors that influence the durability of the homograft
Anforderungen: Early stage researcher or 0-4 yrs (Post graduate)

Abteilung: Chemistry; Inorganic Chemistry
Dauer: 1 y
Aufgaben: The research activity will be focused on the design, synthesis and photo-chemical and photo-physical characterization of novel system for the controlled release of Nitric Oxide (NO) in order to develop a novel molecular platform for the intracellular NO sensing
Anforderungen: Experienced researcher or 4-10 yrs (Post-Doc)

Aufgaben: As a Research Assistant in Epidemiology and Health Data Sciences you will support the analysis and management for studies on our portfolio using routinely collected data mapped to the OMOP Common Data Model. You will contribute to the development of study documentation for our studies, you will use R packages to run a number of pre-specified analyses and you will conduct and support research activities based on your relevant expertise area. You will contribute to publications, scientific reports and journal articles as well as the presentation of data/papers at conferences and other scientific meetings
Anforderungen: You will hold a relevant post-graduate degree in Epidemiology or a related field together with experience in biostatistics and/or health data sciences. Experience in programming statistical analyses, preferably in R and experience in writing scientific documents, e.g. study reports, manuscripts are essential. As are ability to work within multi-disciplinary teams and independently, good communication skills and excellent team working skills. Experience in the analysis or interpretation of OMOP-mapped data, experience in working with electronic medical records/routinely collected/real world data and experience in generating phenotypes are desirable

Abteilung: Medical Sciences; Medicine
Aufgaben: The research collaborator will work on cerebrospinal fluid and plasma biomarkers of synaptic plasticity and neurodegeneration. The aim of the study is to evaluate the role of synaptic markers at different phases of Alzheimer’s disease and in other neurodegenerative conditions. To this, the research collaborator will implement the biobanking at the Neurology Unit and use different innovative techniques (including ELISA, western blotting and SIMOA) to test new synaptic markers in the population. The research collaborator will also evaluate the correlation between biological markers and clinical as well as imaging markers of brain damage
Anforderungen: Early stage researcher or 0-4 yrs (Post graduate)

Aufgaben: Biologie moléculaire: clonage, génotypage; Biologie cellulaire: transformation et sélection de Sordaria; Microscopie: imagerie de la méiose sur tissu vivant; Traiter les données (analyser, interpréter et valider les résultats); Présenter les résultats et réalisations technologiques lors de réunions d’équipes
Anforderungen: Compétences attendues: Connaissances et expériences en biologie moléculaire; Bonnes connaissances en génétiques; Connaissances en imagerie/microscopie seront un plus mais ne sont pas exigées; Maitrise de l'anglais oral et écrit - Niveau B2 (collaboration avec un membre de l'équipe non-francophone); Lecture et compréhension de protocoles et de méthodes issus de publications scientifiques; Rigueur et autonomie, bonne tenue de cahier de laboratoire; Aptitude à travailler en équipe et à s'inscrire dans des projets collectifs
; Merci d'indiquer dans votre CV: ATTENTION: Les CV ne portant pas ces éléments ne seront pas étudiés; votre dernier diplôme obtenu, la date d'obtention, et l'université délivrant le diplôme (ville, pays); votre niveau d'anglais; toutes vos expériences de laboratoires, en précisant; les noms de vos encadrants/superviseurs, le nom de l'institut; la durée; l'année de réalisation du stage/de l'emploi; les coordonnées de deux référents à ...

Aufgaben: Dissection de tissus sur des embryons de souris et de poulet; Coupes histologiques; Marquages histologiques sur coupes ou embryons entiers (immunomarquages, hybridation in situ); Microscopie confocale et à feuille de lumière; Analyse des images, logiciel Imaris et Image J; Biologie moléculaire (PCR, clonage); Culture cellulaire
Anforderungen: Expérience pratique indispensable en histologie (coupes, immunomarquages fluorescents), de l'imagerie et de l'analyse d’images; Expérience pratique indispensable en PCR; Expertise en biologie du développement ou oncologie pédiatrique

Aufgaben: The work will primarily focus on synthesis and subsequent catalysis testing. Initially the focus will be on designing and synthesising coordination complexes and/or organometallic catalysts in combination with polyoxometalates. An important aspect will be the incorporation of suitable cations, including ionic liquids, for the development of solubility-controlled catalysts; The overall aim is to develop efficient catalysts for the production of sustainable polymers, where CO2 will be used as one of the raw materials
Anforderungen: Applicants must hold a master's degree or equivalent education in chemistry; Applicants must have a solid and documented background in either organometallic chemistry or hybrid polyoxometalates, with an emphasis on synthetic methods and the choice of experimental parameters. It is an advantage to have documented competency in both

Aufgaben: At QGG, we are leading research on genetic analysis and breeding value estimation, particularly focusing on feed efficiency and climate-related traits in dairy cattle. Our ongoing projects aim to integrate these crucial traits into routine genetic evaluations for improved breeding outcomes. The primary responsibility of the selected candidate will involve conducting genetic analyses of feed efficiency data to estimate breeding values, thereby enhancing the breeding goals for dairy cattle. Working collaboratively within our team and with external research partners, the candidate will contribute to ongoing projects focused on feed efficiency and methane emission traits in dairy cattle
Anforderungen: Ph.D. degree in quantitative genetics, animal breeding, statistics, or a related field; Proficiency in statistical analysis of genetic data related to feed efficiency in dairy cattle and the ability to develop new genetic models; Experience with one or more scripting languages, such as R, Python, or Perl; Involvement in international networks engaged in dairy cattle efficiency research will be advantageous; A strong work ethic and the de

Aufgaben: The Postdoctoral Research Fellow's tasks will be to research in WP2, on the theoretical robustness of summary measures of population health, such as disability-adjusted life years (DALYs) or quality-adjusted life years (QALYs). Specifically, the candidate will focus on the theoretical and applied aspects concerning summary measures of population health, such as the relationship between death at the individual level and death at the population level, the modeling of lost life years due to premature death, the modeling of stillbirths, the commensurability of morbidity and mortality in summary measures, and policy relevance of different types of mortality measures. The Postdoctoral Research Fellow will participate in ETHME’s research group based at a leading research centre on medical ethics
Anforderungen: Ph.D. in a relevant subject (such as medicine, philosophy, medical ethics, and health economics). Doctoral theses must be submitted for evaluation by the closing date. Appointment is dependent on the public defence of the doctoral thesis being approved