Duties: Réaliser des analyses biochimiques d’échantillons sanguins (ELISA, tests colorimétriques); Réaliser des analyses en biologie moléculaire sur des échantillons sanguins (extraction ADN et ARN, expression de gènes, méthylation); Préparer les cocktails d’éléments traces métalliques; Suivre les oiseaux en expérimentation; Analyser les données issues du suivi RFID des oiseaux; Analyses statistiques descriptives des données de suivi des oiseaux, des résultats des analyses biochimiques et de biologie moléculaire
Requirements: Connaissances et fort intérêt en écophysiologie évolutive et écotoxicologie; Avoir un Master en écotoxicologie et/ou écophysiologie (au début du contrat en août); Formation opérateur en expérimentation animale (au minimum); Manipulation d’oiseaux; Manipulation de pipettes, centrifugeuse et autres matériels de bases d’un laboratoire de biochimie; Rigueur et intérêt pour le travail de paillasse; Analyse statistique des données avec le logiciel R; Connaissances des règles d’hygiène et sécurité pour la manipulation d’éléments traces métalliques; Travailler en équipe; Anglais scientifique de niveau B2 selon le cadre européen commun de référence pour les langues

Duties: Your general tasks will consist of; Independent research of high international quality, including publication; Teaching, guidance and examination of Bachelor’s and Master's degree students, as well as possibly co-supervision of PhD students; Contribution to external research funding; Development of national and international networks and collaborations in research; Your specific tasks will consist of developing a research program on the regulation of nitrogen fixation in legumes
Requirements: Applicants should hold a PhD in plant genetics and have a documented and strong publication record in the field of nitrogen fixation

Duties: L’ingénieur(e) d'étude mènera ses activités au sein du laboratoire Géosciences Rennes et de l'OSUR. Son activité principale sera de développer et optimiser les méthodes et les outils d'étude des processus de colonisation, croissance et communication de bactéries sous écoulement dans des bioréacteurs et dans des systèmes microfluidiques
Requirements: Nous recherchons un ou une canditat.e possédant une excellente maîtrise des méthodes d'étude des interactions entre micro-organismes et écoulement de fluide; en conditions contrôlées. Une expérience en microfluidique avec des micro-organismes est demandée. Le ou la candidat(e) devra avoir un diplôme de master ou équivalent en microfluidique, biophysique, ingénierie biologique, microbiologie ou mécanique des fluides

Duties: Recent improvements in machine learning have dramatically improved the accessibility of de novo protein design. In this project, we seek to exploit these developments to interrogate the role and mechanisms of receptor signalling in neuronal plasticity. The center of Excellence for “Protein in Memory” seeks to understand the molecular basis for memory with an emphasis on protein mechanism. Recent developments in protein structure prediction (e.g. AlphaFold2) and protein de novo design (e.g. RFDiffusion) have opened new possibilities for probing such mechanisms. The project will seek to use existing algorithms to new biological problems and is thus not focused on development of computational methods. We wish to generate small protein binders against a range of important neuroscience targets and use these for mechanistic studies in cellular models
Requirements: The project will involve both experimental and computational work and the candidate is expected to be comfortable with both. The candidate is expected to have (or being close to finishing) a Ph.D. in molecular biology, biochemistry, biophysics, biology, biotechnology, nanoscience or similar, and a good track record of productivity. Experience with some, but not all, of the following topics is an advantage: Recombinant protein expression and purification, biochemical and biophysical protein characterization, protein structure prediction or computational protein design. Furthermore, we expect an interest in interdisciplinarity and good collaboration skills

Duties: The position includes experimental work on the interaction between free radicals (ROS and RNI) produced by activated host cells and the intracellular effect of new antibiotics against Mycobacterium tuberculosis. Methods included are measurement of ROS and RNI via -omics methods, flow cytometry including single-cell analysis and experiments in human macrophages and in a lung tissue model. Genetic and epigenetic effects on M. tuberculosis are also a part of the project which includes bioinformatic analysis. The position will also include design and analysis of experimental data and writing of reports for publication in scientific journals
Requirements: We are searching for a PhD in bioinformatics, molecular biology or microbiology. Documented experience and interest in bioinformatics, preferably within bacteriology and infection experiments in inflammatory cells is a requirement for the position

Duties: The post holder will be responsible for characterising repair factors through structural biology techniques, with a focus on cryo-electron microscopy. Ideal candidates should have expertise in molecular cloning, protein expression, purification, and structural methods, preferably in crystallography and electron microscopy. Knowledge of DNA modification enzymes and a background in DNA damage and repair fields are highly desirable
Requirements: You will be required to have research experience in molecular cloning, cell culturing, cryo-electron microscopy, X-ray crystallography, and protein/complex characterization. A strong record of publishing in reputable journals and contributing to grant proposals is essential. Your role will involve managing research projects, mentoring junior researchers, collaborating internally and externally, and organizing and prioritizing work independently. Excellent written and oral communication skills, including presenting at international symposia and to non-specialist audiences, are also crucial

Duties: The focus of the project is on the functionalization of nanowires with DNA and their subsequent immobilization within DNA nanostructures. These structures will undergo characterization through Atomic Force Microscopy and Transmission Electron Microscopy
Requirements: The candidate should have a PhD degree within the broad field of (bio)chemical sciences and have experimental experience in DNA nanotechnology

Department: Biological Sciences; Laboratory Animal Science
Duties: La febbre neurogenica (FN) è un'ipertermia che non risponde a trattamenti antipiretici e che emerge in risposta a emorragia subaracnoidea. Questo progetto mira a descrivere i centri del sistema nervoso centrale coinvolti nella generazione della FN. Gli obiettivi del progetto verranno raggiunti implementando tecniche elettrofisiologiche con approcci biomolecolari e farmacologici per valutare il ruolo dei modulatori infiammatori nell'insorgenza della NF. Aumentare le nostre conoscenze su questo sistema consentirà la progettazione di un nuovo approccio farmacologico al trattamento della FN. Il richiedente sarà responsabile di: condurre la maggior parte degli esperimenti, completare gli obiettivi del progetto, analizzare i dati, scrivere i risultati per la pubblicazione e presentare i risultati all'incontro nazionale. Il candidato riceverà una formazione diretta dal PI, parteciperà a regolari riunioni di laboratorio e journal club e avrà accesso a tutti i servizi dipartimentali
Requirements: Early stage researcher or 0-4 yrs (Post graduate)

Duties: In this project, we will analyse a replication cohort, to verify the associations identified in the original analysis. Relationships between biomarker levels and existing risk scores, and future CVD development will be investigated. Interesting biomarkers will be selected for functional investigation, using various in vitro cell based systems. Effects of biomarker proteins on cell viability, migration, angiogenesis, thrombosis development and inflammation processes, and others, will be studied
Requirements: Qualification with a candidate medicine, or a master’s degree in biological sciences is required. Prior experience with cell culture-based laboratory projects and related molecular biology techniques, such as Western blot, qPCR, ELISA etc. is required. Prior experience with cardiovasular research projects and endothelial cell culture is beneficial, as is previous work with the analysis of patient samples and use of proteomics techniques. The candidate must be flexible and keen to work as part of a larger team

Duties: You will be engaged in both laboratory experiments and bioinformatics analyses of multi-omics datasets generated from host-parasite model systems and environmental samples. Major part of this position will focus on analysis of host-virus dynamics and identifying the functional basis of their interactions but also includes working on other types of parasitic interactions in the lake ecosystem. The research includes fieldwork for lake sampling and sample processing as well as experimental manipulations in the laboratory, cultivation of the host and isolation of parasites, alternative analytical methods, multi-omics analyses and scientific communication
Requirements: A PhD degree (or equivalent) with specialization in microbiology, microbial ecology, molecular biology, bioinformatics or related areas; Proficiency in English speaking and writing; An analytical mind set and a keen interest in aquatic microbial ecology and phage genome evolution; A strong track record of scholar publications; Expertise in multi-omics analysis of microbes; Experience with field work and processing water samples

Duties: You will be responsible for undertaking advanced academic study to underpin lectures and class teaching as well as lecture, tutor, (conduct practical classes using laboratory or workshop equipment), and supervise undergraduate and postgraduate students. You will be tasked with managing independent research projects or specific areas of research within a broad programme, to include: developing research questions within a specific context; conducting original research; analysing qualitative and/or quantitative data from a variety of sources, and developing appropriate analytical protocols and techniques to support research. You will also be responsible for liaising with examiners and academic staff regarding student performance and the development of new modules, and with funding bodies, stakeholders, and researchers in related fields to share information and expertise
Requirements: To be successful in this role, you will hold a relevant DPhil degree in a topic related to global health modelling, together with post-qualification experience. You will have expertise in infectious disease modelling and analytical techniques and demonstrate an interest in modelling for global health, and you will have experience with developing and delivering teaching as well as sufficient depth and breadth of knowledge in infectious disease modelling to develop course units

Department: Medical Sciences; Medicine
Duties: Pulmonary homografts is commonly used for RVOT reconstruction in congenital heart surgery. These conduits demonstrate reasonable outcomes in terms of hemodynamics, low thromboembolic risk and a better resistance to infection. However, there are some limiting factors associated with the use of homografts: availability, variability of duration and the inflammatory response. Several studies demonstrated the association between the characteristics of the donor, the method of preservation of the homograft, inflammatory response patient related and the degeneration of the conduit. Specifically, there is a consistent association between blood group and HLA-DR mismatch, short antibiotic preservation time and homograft valve failure; The impact of the inflammatory response on the surgical outcome after implantation of a pulmonary homograft represents an interesting topic of study to better understand the factors that influence the durability of the homograft
Requirements: Early stage researcher or 0-4 yrs (Post graduate)

Duties: As a Research Assistant in Epidemiology and Health Data Sciences you will support the analysis and management for studies on our portfolio using routinely collected data mapped to the OMOP Common Data Model. You will contribute to the development of study documentation for our studies, you will use R packages to run a number of pre-specified analyses and you will conduct and support research activities based on your relevant expertise area. You will contribute to publications, scientific reports and journal articles as well as the presentation of data/papers at conferences and other scientific meetings
Requirements: You will hold a relevant post-graduate degree in Epidemiology or a related field together with experience in biostatistics and/or health data sciences. Experience in programming statistical analyses, preferably in R and experience in writing scientific documents, e.g. study reports, manuscripts are essential. As are ability to work within multi-disciplinary teams and independently, good communication skills and excellent team working skills. Experience in the analysis or interpretation of OMOP-mapped data, experience in working with electronic medical records/routinely collected/real world data and experience in generating phenotypes are desirable

Department: Medical Sciences; Medicine
Duties: The research collaborator will work on cerebrospinal fluid and plasma biomarkers of synaptic plasticity and neurodegeneration. The aim of the study is to evaluate the role of synaptic markers at different phases of Alzheimer’s disease and in other neurodegenerative conditions. To this, the research collaborator will implement the biobanking at the Neurology Unit and use different innovative techniques (including ELISA, western blotting and SIMOA) to test new synaptic markers in the population. The research collaborator will also evaluate the correlation between biological markers and clinical as well as imaging markers of brain damage
Requirements: Early stage researcher or 0-4 yrs (Post graduate)

Duties: Biologie moléculaire: clonage, génotypage; Biologie cellulaire: transformation et sélection de Sordaria; Microscopie: imagerie de la méiose sur tissu vivant; Traiter les données (analyser, interpréter et valider les résultats); Présenter les résultats et réalisations technologiques lors de réunions d’équipes
Requirements: Compétences attendues: Connaissances et expériences en biologie moléculaire; Bonnes connaissances en génétiques; Connaissances en imagerie/microscopie seront un plus mais ne sont pas exigées; Maitrise de l'anglais oral et écrit - Niveau B2 (collaboration avec un membre de l'équipe non-francophone); Lecture et compréhension de protocoles et de méthodes issus de publications scientifiques; Rigueur et autonomie, bonne tenue de cahier de laboratoire; Aptitude à travailler en équipe et à s'inscrire dans des projets collectifs
; Merci d'indiquer dans votre CV: ATTENTION: Les CV ne portant pas ces éléments ne seront pas étudiés; votre dernier diplôme obtenu, la date d'obtention, et l'université délivrant le diplôme (ville, pays); votre niveau d'anglais; toutes vos expériences de laboratoires, en précisant; les noms de vos encadrants/superviseurs, le nom de l'institut; la durée; l'année de réalisation du stage/de l'emploi; les coordonnées de deux référents à ...

Duties: Dissection de tissus sur des embryons de souris et de poulet; Coupes histologiques; Marquages histologiques sur coupes ou embryons entiers (immunomarquages, hybridation in situ); Microscopie confocale et à feuille de lumière; Analyse des images, logiciel Imaris et Image J; Biologie moléculaire (PCR, clonage); Culture cellulaire
Requirements: Expérience pratique indispensable en histologie (coupes, immunomarquages fluorescents), de l'imagerie et de l'analyse d’images; Expérience pratique indispensable en PCR; Expertise en biologie du développement ou oncologie pédiatrique

Duties: At QGG, we are leading research on genetic analysis and breeding value estimation, particularly focusing on feed efficiency and climate-related traits in dairy cattle. Our ongoing projects aim to integrate these crucial traits into routine genetic evaluations for improved breeding outcomes. The primary responsibility of the selected candidate will involve conducting genetic analyses of feed efficiency data to estimate breeding values, thereby enhancing the breeding goals for dairy cattle. Working collaboratively within our team and with external research partners, the candidate will contribute to ongoing projects focused on feed efficiency and methane emission traits in dairy cattle
Requirements: Ph.D. degree in quantitative genetics, animal breeding, statistics, or a related field; Proficiency in statistical analysis of genetic data related to feed efficiency in dairy cattle and the ability to develop new genetic models; Experience with one or more scripting languages, such as R, Python, or Perl; Involvement in international networks engaged in dairy cattle efficiency research will be advantageous; A strong work ethic and the de

Duties: The Postdoctoral Research Fellow's tasks will be to research in WP2, on the theoretical robustness of summary measures of population health, such as disability-adjusted life years (DALYs) or quality-adjusted life years (QALYs). Specifically, the candidate will focus on the theoretical and applied aspects concerning summary measures of population health, such as the relationship between death at the individual level and death at the population level, the modeling of lost life years due to premature death, the modeling of stillbirths, the commensurability of morbidity and mortality in summary measures, and policy relevance of different types of mortality measures. The Postdoctoral Research Fellow will participate in ETHME’s research group based at a leading research centre on medical ethics
Requirements: Ph.D. in a relevant subject (such as medicine, philosophy, medical ethics, and health economics). Doctoral theses must be submitted for evaluation by the closing date. Appointment is dependent on the public defence of the doctoral thesis being approved

Duties: This developmental role provides an opportunity for you to deliver excellent student experience on international health of our intercalated undergraduate and taught postgraduate programmes. You will have the opportunity to deliver lectures, practical sessions and tutorials as well as supporting in leading a module and being involved in the assessment, supervision and mentoring of students. You will be student centred in your approach and be able to provide academic support to students
Requirements: Applicants will have a postgraduate or equivalent qualification who has just completed or about to complete PhD in related fields of health, public health or health systems and have previous international experience, especially in low-middle income countries. You should have experience of developing and delivering your own teaching using a range of materials and methods and be able to demonstrate experience of student assessment and giving feedback. You will also have excellent computer and IT skills, with effective communication, interpersonal and presentation skills. Experience in undertaking administrative duties will also be an advantage

Duties: The main aim of the project the post-holder will join is to develop, improve and apply models for improving situational awareness and informing data collection in outbreaks via data analysis and forecasting. Including systematic assessment of the predictive ability of any forecasts made, and whether the inclusion of individual, spatial, behavioural or genetic data can improve them. There is considerable freedom for work within the aims of the project and scope for the development and use of state-of-the-art methodology and computation with direct impact on public health
Requirements: The successful applicant will have a postgraduate degree, ideally a doctoral degree in a quantitative discipline such as epidemiology, mathematics, physics, statistics, bioinformatics or computational biology, or similar research experience. Candidates should have proficient knowledge of a programming language for mathematical or statistical modelling, including some experience with R, and be committed to open research and/or software development. Experience in outbreak analysis or model-based forecasting is an advantage

Duties: Identify and recruit eligible participants by collaborating with ophthalmology and local optometry clinics; Provide informed consent to potential participants to ensure understanding of the research aims, procedures, risks, and benefits; Coordinate ophthalmic clinical activities including appointment scheduling, follow-up visits, and communication with research patients; Collect and manage accurate clinical data from patient interactions, and follow-up assessments, ensuring data integrity and confidentiality
Requirements: A degree level qualification in a relevant area or an equivalent combination of relevant experience and/or education/training; Experience in Ophthalmic Clinical assessment is desirable but not essential; Excellent organisational skills, with the ability to be self-directed and use initiative and record-keeping skills appropriate to carrying out a scientific investigation; Excellent communication and interpersonal skills, with the ability to interact effectively with a range of people and organisations

Duties: As the Research Fellow, you will undertake research and project-related activities under the broad direction of the project Chief Investigators for the project entitled “Co-designing a consumer-focused digital health system to improve adverse drug event (ADE) detection, management and reporting”. This project is focused on the development of a co-designed digital tool to enable consumers and health care professionals to actively detect and manage adverse drug events
Requirements: PhD qualification in Pharmacy; Demonstrated understanding of qualitative research techniques associated with co-design of health care systems; Understanding of confidentiality and privacy laws as relates to the use of medical and health related data; Demonstrated competency in recording, analysing, presenting and disseminating research to stakeholders including the preparation of papers for high quality publications or posters for conference presentations

Duties: iTHEMS is seeking postdoctoral researcher(s) in ecology, evolutionary biology, and biodviersity. The successful applicants are expected to work on theoretical studies on biodiversity changes under environmental variability. Also, such applicants are expected to engage in interdisciplinary interactions and collaborations among different fields such as mathematics, physics, chemistry, biology, information sciences, computational sciences, and social sciences, under the concept of iTHEMS. For more details, send an email to the contact address below
Requirements: The candidate should possess or is expected to obtain a doctoral degree by the starting date

Workload: 50-70%
Duties: Sie begleiten unsere Patient*innen zuverlässig und mit Feingefühl durch die Therapie; Sie sind verantwortlich für die Durchführung von Befunden, der Zielvereinbarung von Behandlungen und die Kontrolle der Therapieerfolge; Sie betreuen die Verlaufsdokumentation; Sie kooperieren in enger Zusammenarbeit mit den Fachärzten aus der Urologie, Gynäkologie und Proktologie
Requirements: Sie sind dipl. Physiotherapeut* HF/FH mit einer Weiterbildung in Urogenitalrehabilitation; Ihr gutes Einfühlungsvermögen hilft Ihnen bei der Betreuung und Beratung von Patient*innen, den Angehörigen sowie Mitarbeitenden; Sie legen Wert auf eine interdisziplinäre Zusammenarbeit und geben Ihr Wissen und Erfahrungen mit Freude an Ihre Kolleg*innen weiter; Sie verfügen über sehr gute Deutschkenntnisse in Wort und Schrift; Ihre administrative Expertise und PC-Kenntnisse runden Ihr Profil ab

Duties: Bearbeitung von Humanproben zum Nachweis von Bakterien, Pilzen und Parasiten; Erstellung von Antibiogrammen; Technische Befundvalidierung
Requirements: Abgeschlossenes Bachelor-Studium der Biomedizinischen Analytik oder gleichwertige Ausbildung (BMA); Abschluss einer naturwissenschaftlichen oder technischen Ausbildung auf Bachelor-Niveau; Eintragung in das Gesundheitsberuferegister (BMA); Teamfähigkeit und Selbstständigkeit; Engagement und Flexibilität; Bereitschaft zu Spät- und Wochenenddiensten