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Position: Postdoc in NMR based structural studies of RNA riboswitches
Institution: Technical University of Denmark
Location: Kongens Lyngby, Lyngby‐Taarbæk Municipality, Denmark
Duties: The position offers an opportunity to work with a dynamic and multi-disciplinary project. You will carry out research in a team engaged in multiple NMR projects in the field of RNA structural studies, fragment-based drug discovery screening and studies of interactions with their targets (RNA or protein), natural product, the identification of new structural scaffolds and in-situ NMR based metabolomics. The research project will provide opportunities to synthesize RNA using both in vitro transcription and chemically, preform NMR based structural elucidation of the fluorine responsive riboswitch apo and holo form as well as study the dynamic and kinetic structural impact of different ligands and ions on RNA structures. In this position you will also have opportunities to work with undergraduate and graduate students
Requirements: As a formal qualification, you must hold a PhD degree (or equivalent) in structural biology or chemical biology and a strong theoretical and experimental background in NMR spectroscopy and knowledge within structural biology
   
Text: Postdoc in NMR based structural studies of RNA riboswitches The position offers an opportunity to work with a dynamic and multi-disciplinary project. You will carry out research in a team engaged in multiple NMR projects in the field of RNA structural studies, fragment-based drug discovery screening and studies of interactions with their targets (RNA or protein), natural product, the identification of new structural scaffolds and in-situ NMR based metabolomics. The research project will provide opportunities to synthesize RNA using both in vitro transcription and chemically, preform NMR based structural elucidation of the fluorine responsive riboswitch apo and holo form as well as study the dynamic and kinetic structural impact of different ligands and ions on RNA structures. In this position you will also have opportunities to work with undergraduate and graduate students As a formal qualification, you must hold a PhD degree (or equivalent) in structural biology or chemical biology and a strong theoretical and experimental background in NMR spectroscopy and knowledge within structural biology
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