Bioinformatics Position in Gene Expression and Chromatin Epigenetics Analysis | Basel, Switzerland | Friedrich Miescher Institute for Biomedical Research

Position:	Bioinformatics Position in Gene Expression and Chromatin Epigenetics Analysis
Institution:	Friedrich Miescher Institute for Biomedical Research
Location:	Basel, Switzerland
Duties:	The successful candidate will work on the computational analysis of large datasets from high throughput sequencing technologies and provide bioinformatics support for the Rijli group
Requirements:	Candidates should have a PhD in Computational Biology, Physics, Computer Science, or similar, or in a relevant biological field with quantitative/computational experience. We expect a track record in analyzing high-throughput sequencing data and a strong interest in gene regulation and epigenetics

Text:	Bioinformatics Position in Gene Expression and Chromatin Epigenetics Analysis A Position in Bioinformatics/Computational Biology is available in the research group of Prof. Filippo Rijli at the Friedrich Miescher Institute for Biomedical Research (FMI) in Basel, Switzerland. The candidate will be embedded in the FMI Bioinformatics Platform-Swiss Institute of Bioinformatics and co-supervised by the Head of the FMI Computational Biology group, Dr. Michael Stadler. The successful candidate will work on the computational analysis of large datasets from high throughput sequencing technologies and provide bioinformatics support for the Rijli group. Candidates should have a PhD in Computational Biology, Physics, Computer Science, or similar, or in a relevant biological field with quantitative/computational experience. We expect a track record in analyzing high-throughput sequencing data and a strong interest in gene regulation and epigenetics. Supported by ERC and SNF grants, the Rijli group investigates the role of transcription and epigenetic factors in chromatin regulation during mouse craniofacial and brain circuit development as well as human cartilage regeneration and repair (e.g. see Science 2006 , 2013 , 2017 ; Cell Rep 2015 , 2017 , 2020 ; Nature Genetics 2021 ). We are currently mapping chromatin states and generating 3D genome maps of identified neuronal subsets and cranial neural crest cell subpopulations. We aim at gaining a systems-level understanding of the regulatory principles of chromatin modifications in gene regulation by integrating available genetic, epigenetic, and expression data from high throughput sequencing technologies (including single cell and bulk RNAseq, single cell and bulk ATACseq, ChIPseq, promoter capture Hi-C-seq, etc.). The successful candidate will join two computational scientists (a postdoc and a PhD student) already embedded in the Rijli group. The position is available immediately. The initial contract will be for 2 years, with a plan for extension. Applications should be submitted at www.fmi.ch/opening and include a motivation letter, CV with research experience and interests, and the contact details of three referees. After an initial selection based on credentials and qualifications, shortlisted candidates will be invited for an interview, starting early January 2023. For further information please contact Filippo Rijli ( filippo.rijli@fmi.ch ). The FMI - affiliated with the University of Basel and the Novartis Institutes for Biomedical Research - is a world-class biomedical research institute dedicated to understanding the molecular mechanisms of health and disease, and to training early-career scientists. It is based in the vibrant city of Basel, Switzerland, which offers an exceptional scientific and cultural environment.