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Position: Analytical Scientist - Statistical and Clinical Genomics
Institution: Institute of Cancer Research
Location: London, United Kingdom
Duties: We are seeking an analytical scientist with experience in biomedical statistics to join the Breast Cancer Research Bioinformatics Group at the Breast Cancer Now Centre (ICR, South Kensington site, London). Our goal is to use cutting-edge data-mining techniques in collaboration with experimental investigators to identify new molecular markers of breast cancer. Resultant markers will be validated by co-investigators at the centre and at the clinical trials unit of the ICR. You will work in an interdisciplinary team of data scientists who are experts in genomic data analysis, machine learning and software development; thereby offering unique development opportunities. For the most part, your work will focus on (however not limited to) integrating genomics and clinical datasets from breast cancer clinical cohorts and trials. In particular, focussing on in-house trials investigating DNA repair pathways and mechanisms of PARP inhibitor sensitivity and resistance
Requirements: Applicants should hold a degree in a computational/numerical subject, have programming and scripting experience, and posses basic knowledge of biology. It is essential to hold a post-graduate qualification in biostatistics or have gained significant experience within a biostatistics role(s)
   
Text: Skip to content Toggle navigation Making the discoveries that defeat cancer Donate now Making the discoveries that defeat cancer Donate now Login | Register Toggle navigation Home Current Vacancies Help Center Analytical Scientist - Statistical and Clinical Genomics Closing Date 24/10/2021, 23:55 Location London Division Breast Cancer Research Team Breast Cancer Research Bioinformatics Group Vacancy Type Full time Type of Contract Fixed Term Length of Contract 3 years Hours per Week 35 Salary Range £32,000 - £44,400 The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.The ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top five cancer centres globally.The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission - to make the discoveries that defeat cancer. Vacancy Description We are seeking an analytical scientist with experience in biomedical statistics to join the Breast Cancer Research Bioinformatics Group at the Breast Cancer Now Centre (ICR, South Kensington site, London). Our goal is to use cutting-edge data-mining techniques in collaboration with experimental investigators to identify new molecular markers of breast cancer. Resultant markers will be validated by co-investigators at the centre and at the clinical trials unit of the ICR.You will work in an interdisciplinary team of data scientists who are experts in genomic data analysis, machine learning and software development; thereby offering unique development opportunities. For the most part, your work will focus on (however not limited to) integrating genomics and clinical datasets from breast cancer clinical cohorts and trials (e.g. PMIDs: 29713086, 34081848, 33098992, 30420699). In particular, focussing on in-house trials investigating DNA repair pathways and mechanisms of PARP inhibitor sensitivity and resistance.You will perform routine statistical analysis to assess data quality and statistical methods to correlate genomic datasets with clinical variables. The resulting findings will lead to the development and validation of new hypotheses using in-vitro and in-vivo experiments in collaboration with wet-lab scientists in the division. You will have opportunities to optimise/extend our existing computational pipelines and where necessary, develop new statistical methods for the analysis and interpretation of big data in breast cancer. The successful appointee is also expected to play a key role in liaising with clinical and wet-lab scientists, as well as write up of research results in a highly collaborative environment.Applicants should hold a degree in a computational/numerical subject, have programming and scripting experience, and posses basic knowledge of biology. It is essential to hold a post-graduate qualification in biostatistics or have gained significant experience within a biostatistics role(s).This position is offered on a fixed term 3 year contract. Starting salary is in the range of £32,000 to £44,400 per annum inclusive based on previous experience. We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview. However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.The ICR is the leading academic research centre in the UK. Effective industry collaboration and innovation in new medicines and technologies are at the heart of our approach to drive benefits for patients. The ICR is ranked: first for the quality and impact of our research*second worldwide for the number of our publications cited in patents**fourth worldwide for the citation rate of scientific research published across all fields**fourth worldwide for top-cited research publications**in the top five higher education institutions worldwide for academic influence and commercial impact** *2014 Research Excellence Framework** U-Multirank, 2020 Funded by Job Description and Person Specification Analytical Scientist - Statistical and Clinical Genomics (Sept 2021) .pdf - 516KB Additional Documentation for Candidates View cookie / data protection and privacy policy  Facebook  Twitter  LinkedIn  RSS Terms and conditions Privacy Cookies Accessibility Copyright © 2016 The Institute of Cancer Research. All rights reserved.
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