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Position: PhD Studentship in Developing Bioengineered RNA Nanoparticles for Applications in Surgery and Interventional Science
Institution: University College London
Department: Division of Surgery & Interventional Science - Research Department of Surgical Biotechnology
Location: London, United Kingdom
Duties: Our research group specialises in the development of new technologies for gene and cell therapy, with specific emphasis on engineering virus-like particles (VLPs) for delivery of RNA into target cells. During this PhD studentship, the student will engineer novel VLPs designed to treat diseases requiring liver surgery, such as viral hepatitis and hepatocellular carcinoma. The student will investigate new technologies engineered with features that harness the immune system for targeted killing of cancer cells or virally infected cells. Techniques will include molecular engineering of viral constructs, analysis of vector potency, development of ex vivo organoid cultures and in vivo investigation of therapeutic efficacy
Requirements: BSc (or equivalent) in biological/medical sciences; Prior knowledge of gene therapy technologies or molecular virology; Good organisational skills and attention to detail; Effective spoken and written English; Willingness to learn and adapt to new techniques
   
Text: PhD Studentship in Developing Bioengineered RNA Nanoparticles for Applications in Surgery and Interventional Science , - Ref:1879127 Click here to go back to search results UCL Department / Division Division of Surgery & Interventional Science Specific unit / Sub department Research Department of Surgical Biotechnology Location of position London Duration of Studentship 3 years Stipend £17,609 per annum with annual incremental increases ( UK fees, open to students eligible for home fees only) Vacancy Information A PhD studentship is available with 3 years stipend funding at the UCL Division of Surgery and Interventional Science under the supervision of Dr John Counsell and Dr Gavin Jell. Studentship Description Our research group specialises in the development of new technologies for gene and cell therapy, with specific emphasis on engineering virus-like particles (VLPs) for delivery of RNA into target cells. During this PhD studentship, the student will engineer novel VLPs designed to treat diseases requiring liver surgery, such as viral hepatitis and hepatocellular carcinoma. The student will investigate new technologies engineered with features that harness the immune system for targeted killing of cancer cells or virally infected cells. Techniques will include molecular engineering of viral constructs, analysis of vector potency, development of ex vivo organoid cultures and in vivo investigation of therapeutic efficacy. Person Specification Essential: BSc (or equivalent) in biological/medical sciences. Prior knowledge of gene therapy technologies or molecular virology. Good organisational skills and attention to detail. Effective spoken and written English. Willingness to learn and adapt to new techniques. Desirable: MSc in a relevant subject area. Practical experience with gene therapy technologies and molecular virology. Experienced in analysing and writing up data into research reports. Experienced in presenting complex information effectively to a range of audiences. Evidence of a long-term focus towards developing a research career in academia and/or industry. Eligibility The studentship covers only the fees for UK students. Additional fees may be required for students applying who do not fulfil the criteria for UCL home students. Please check the UCL website for full criteria at http://www.ucl.ac.uk/current-students/money/fees-support/fee_status_proc . To make an application, please email your CV and a covering letter to: Dr John Counsell ( j.counsell@ucl.ac.uk ) explaining your interests and research experience (including examples of previous project work). Contact name Dr John Counsell Contact details j.counsell@ucl.ac.uk UCL Taking Action for Equality Closing Date 29 Oct 2021 Latest time for the submission of applications 23:59 Interview date 15th November 2021 Studentship Start Date 1st January 2022
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