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Position: Postdoctoral Fellow
Institution: Paul Scherrer Institut
Location: Villigen, Aargau, Switzerland
Duties: Identify and develop new targets within the portfolio of our industry partner; Expression and large-scale crystallization of G protein-coupled receptors; Characterization of synthetic photoactive ligands and their complexes with GPCR’s; Time-resolved serial crystallographic data collection; General support of these areas at leadXpro, LBR, SLS and SwissFEL
Requirements: We expect a completed PhD in Biochemistry, Biology or Physics with additional post-doctoral education as an extra qualification. The ideal candidate is a structural biologist with experience in the expression and crystallization of G protein-coupled receptors. Additional knowledge in the design of ligands that can be activated with light, pharmacology of GPCR’s, experience in time-resolved spectroscopy and ligand binding assays is of advantage
   
Text: Skip to main content Paul Scherrer Institut PSI PSI Research, Labs & User Services Digital User Office Digital User Office DE EN FR MENU Suche Suche Suche Hauptnavigation Our Research Open mainmenu item Current topics from our research Matter and Material Human Health Energy and Environment Large Research Facilities Brochures 5232 — The PSI magazine Industry Open mainmenu item Overview Technology Transfer Expertise Spin-off Companies Park Innovaare Proton Therapy Open mainmenu item Overview Physician & Patient Information Career Open mainmenu item Overview Job Opportunities Working at PSI Personnel Policy Training and Further Education Vocational Training PSI Education Centre Support Program "PSI Career Return Program" PSI-FELLOW/COFUND Visit to PSI Open mainmenu item Overview Visitor Centre psi forum Schülerlabor iLab Public Events How to find us About PSI Open mainmenu item PSI in brief Strategy Guiding principles Facts and figures Organisational structure Für die Medien Suppliers and customers Customers E-Billing Contact Suche Suche DE EN FR Digital User Office (mobile) Digital User Office You are here: PSI Home Education and Jobs Job Opportunities Postdoctoral Fellow Secondary navigation Education and Jobs Job Opportunities Expanded submenu item Our application process at a glance Jobmail Spontaneous application Further Positions in the ETH Domain Personnel Policy Open submenu item Principles Collaboration and leadership Human Resources Development HRS4R Working at PSI Open submenu item Employment Conditions Social Benefits Further positive points Corporate Social Responsibility Training and Further Education Open submenu item Higher Education Vocational Training School Lab High-school matricu­lation projects PSI Education Centre Support Program "PSI Career Return Program" Open submenu item Eligibility Criteria Members of the evaluation committee PSI-FELLOW/COFUND - International Fellowship Programme for Postdocs Useful links Equal Opportunities, Diversity & Inclusion Homepage PSI Education Centre Homepage Vocational Training Homepage Career Center The Paul Scherrer Institute PSI is the largest research institute for natural and engineering sciences within Switzerland. We perform cutting-edge research in the fields of matter and materials, energy and environment and human health. By performing fundamental and applied research, we work on sustainable solutions for major challenges facing society, science and economy. PSI is committed to the training of future generations. Therefore, about one quarter of our staff are post-docs, post-graduates or apprentices. Altogether, PSI employs 2100 people. You will identify and develop membrane protein targets for time-resolved structural interaction mapping of drug binding together with our industrial partner leadXpro. You will work on purification and crystallization of the protein and characterize binding of synthetic photoactive ligands to modulate G protein-coupled receptor function. Within an interdisciplinary team of scientists, you will support our efforts in establishing time-resolved serial crystallography at the Swiss Light Source and the Swiss X-Ray Free Electron Laser. For a position in the time-resolved Structural Biology Group in the Laboratory of Biomolecular Research (LBR) we are looking for a Postdoctoral Fellow Biochemist Your tasks Identify and develop new targets within the portfolio of our industry partner Expression and large-scale crystallization of G protein-coupled receptors Characterization of synthetic photoactive ligands and their complexes with GPCR’s Time-resolved serial crystallographic data collection General support of these areas at leadXpro, LBR, SLS and SwissFEL Your profile We expect a completed PhD in Biochemistry, Biology or Physics with additional post-doctoral education as an extra qualification. The ideal candidate is a structural biologist with experience in the expression and crystallization of G protein-coupled receptors. Additional knowledge in the design of ligands that can be activated with light, pharmacology of GPCR’s, experience in time-resolved spectroscopy and ligand binding assays is of advantage. We offer Our institution is based on an interdisciplinary, innovative and dynamic collaboration. You will profit from a systematic training on the job, in addition to personal development possibilities and our pronounced vocational training culture. If you wish to optimally combine work and family life or other personal interests, we are able to support you with our modern employment conditions and the on-site infrastructure. Your employment contract is limited to 2 years. For further information, please contact Dr Jörg Standfuss, phone 41 56 310 25 86. Please submit your application online by 30. April 2021 (including list of publications and addresses of referees) for the position as a Postdoctoral Fellow (index no. 2316-00). Paul Scherrer Institut, Human Resources Management, Silja Giacomini-Diebold, 5232 Villigen PSI, Switzerland Apply online now Open sharing options top Footer Paul Scherrer Institut Forschungsstrasse 111 5232 Villigen PSI Switzerland Telephone: 41 56 310 21 11 Telefax: 41 56 310 21 99 How to find us Contact form Visitor Centre psi forum School Lab iLab (in German) Center for Proton Therapy PSI Education Centre PSI Guest House PSI Gastronomie (in German) Service & Support Phone Book/People Search User Office Accelerator Status PSI Publications Suppliers E-Billing Computing Safety (in German) Career Working at PSI Job Opportunities Training and further education Vocational Training (in German) PSI Education Center For the media PSI in brief Facts and Figures Media Contact Media Releases Social Media Newsroom Follow us: Twitter (in English) LinkedIn Youtube Issuu RSS Footer legal Imprint Terms and Conditions Editors' login
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