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Position: Research Fellow
Institution: University College London
Department: UCL Cancer Institute - Research Department of Haematology
Location: London, United Kingdom
Duties: This role will involve working across the myeloma and immunotherapy labs in UCL to drive the above project, You will develop new approaches to CAR-T design based on rational modulation of T cell function, and evaluate CAR-T cell activity using in vitro and in vivo models. You will work within the CAR-T group, and the wider myeloma laboratory, to investigate the tumour immune environment in the myeloma bone marrow, using high dimensional flow cytometry, single cell and bulk sequencing, and TCR sequencing and be highly experienced in flow cytometry, including the design of high dimensional panels, molecular biology, and have an understanding of cancer immunology. You will also be required to set up new platforms as required for the successful execution of the project
Requirements: The candidate must possess a BSc in biomedical sciences or a related subject, >2: 1, a PhD in related subject with laboratory experience and must have submitted thesis prior to interview. The candidate is also expected to have extensive experience in in vitro coculture experiments, experience to design and run murine models as well as experience in multiparametric flow cytometry (independent panel design and optimisation, > 10 colours.)
   
Text: Research Fellow, - Ref:1873980 Click here to go back to search results Apply Now UCL Department / Division UCL Cancer Institute Specific unit / Sub department Research Department of Haematology Location of position London Grade 7 Hours Full Time Salary (inclusive of London allowance) £36,028 - £43,533 per annum Duties and Responsibilities This role will involve working across the myeloma and immunotherapy labs in UCL to drive the above project, You will develop new approaches to CAR-T design based on rational modulation of T cell function, and evaluate CAR-T cell activity using in vitro and in vivo models. You will work within the CAR-T group, and the wider myeloma laboratory, to investigate the tumour immune environment in the myeloma bone marrow, using high dimensional flow cytometry, single cell and bulk sequencing, and TCR sequencing and be highly experienced in flow cytometry, including the design of high dimensional panels, molecular biology, and have an understanding of cancer immunology. You will also be required to set up new platforms as required for the successful execution of the project. The candidate will be required to drive and direct a project to optimise CAR-T therapy for myeloma, to be involved in the design and execution of complex co culture experiments, to oversee the analysis of patient samples, to oversee technicians and students in the team. the candidate will also be expected to attend research seminars and other departmental meetings as required, to participate in any laboratory duties commensurate with the grade as required. The candidate will also be expected to be aware to be aware of and act upon: Disciplinary procedure and Disciplinary rules Grievance procedure Section 7 and 8 of the Health and Safety at Work Act Departmental Fire Guidelines Equal Opportunities Policy and to comply with the Health & Safety regulations of the department. The duration of the post is 24 months in the first instance. Key Requirements The candidate must possess a BSc in biomedical sciences or a related subject, > 2:1, a PhD in related subject with laboratory experience and must have submitted thesis prior to interview. The candidate is also expected to have extensive experience in in vitro coculture experiments, experience to design and run murine models as well as experience in multiparametric flow cytometry (independent panel design and optimisation, > 10 colours.). The candidate is required to be fully able to work in a team, be approachable, able to collaborate with team members and collaborators, to have good organizational skills (of own time and team members), evidence demonstrating ability to work independently, use own initiative and drive decision making and to be highly motivated to succeed in research. Further Details A job description and person specification can be accessed at the bottom of this page. To apply click the APPLY NOW button at bottom of this page. For enquiries regarding the application process please contact Cancer Institute HR Office ci.hr-office@ucl.ac.uk UCL Taking Action for Equality Closing Date 27 Jan 2021 Latest time for the submission of applications 23:59 Interview date TBC Our department holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality. This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff. Please use these links to find out more about UCL working life including the benefits we offer and UCL Terms and Conditions related to this job. JD Research Fellow Apply Now
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