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Position: Research Fellow
Institution: University College London
Department: UCL Queen Square Institute of Neurology - Alzheimer's Research UK - Drug Discovery Institute
Location: London, United Kingdom
Duties: The Alzheimer's Research UK Drug Discovery Institute (ARUK UCL DDI), located at UCL, is a team of neurobiologists, screening scientists and medicinal chemists who have the goal of finding new therapies for neurodegenerative disease. As part of the UCL Queen Square Institute of Neurology, it is integrated into the world-renowned UCL Neuroscience community and aligned with the Dementia Research Institute at UCL. Academic scientists supporting the activites of the ARUK UCL DDI are Institute of Neurology Professors Giampietro Schiavo and John Hardy; A position is available as part of this novel and exciting initiative. You will play a key role in developing and running novel target-based drug discovery assays, and also phenotypic screening assays with imaging, functional or molecular endpoints. There will be a particular focus upon therapeutic modulation of astrocyte and microglial cells. Phenotypic screens may use iPSC derived neural model systems. You will utilise both compound and siRNA libraries
Requirements: Applicants should have an honours degree (minimum 2: 1) and a PhD (or be close to obtaining) or equivalent experience in a biological science topic, plus experience in the design, development and implementation of compound screening assays and/or siRNA screening assays, across different assay platforms from cell-based to cell-free. Excellent oral and written communication skills and good inter-personal skills with an ability to work cooperatively in a multidisciplinary setting are also required. Experience of working in a drug discovery setting (pharma, biotech, academic drug discovery centre) is desirable
   
Text: Research Fellow, - Ref:1871994 Click here to go back to search results Apply Now UCL Department / Division UCL Queen Square Institute of Neurology Specific unit / Sub department Alzheimer's Research UK - Drug Discovery Institute Location of position London Grade 7 Hours Full Time Salary (inclusive of London allowance) £36,028 - £43,533 per annum Duties and Responsibilities The Alzheimer's Research UK Drug Discovery Institute (ARUK UCL DDI), located at UCL, is a team of neurobiologists, screening scientists and medicinal chemists who have the goal of finding new therapies for neurodegenerative disease. As part of the UCL Queen Square Institute of Neurology, it is integrated into the world-renowned UCL Neuroscience community and aligned with the Dementia Research Institute at UCL. Academic scientists supporting the activites of the ARUK UCL DDI are Institute of Neurology Professors Giampietro Schiavo and John Hardy. A position is available as part of this novel and exciting initiative. You will play a key role in developing and running novel target-based drug discovery assays, and also phenotypic screening assays with imaging, functional or molecular endpoints. There will be a particular focus upon therapeutic modulation of astrocyte and microglial cells. Phenotypic screens may use iPSC derived neural model systems. You will utilise both compound and siRNA libraries. The post is available from 1 November 2020 and funded by a grant from ARUK for one year or the period to 31 October 2021, whichever is the shorter, in the first instance, with possibility of renewal. Key Requirements Applicants should have an honours degree (minimum 2:1) and a PhD (or be close to obtaining) or equivalent experience in a biological science topic, plus experience in the design, development and implementation of compound screening assays and/or siRNA screening assays, across different assay platforms from cell-based to cell-free. Excellent oral and written communication skills and good inter-personal skills with an ability to work cooperatively in a multidisciplinary setting are also required. Experience of working in a drug discovery setting (pharma, biotech, academic drug discovery centre) is desirable. Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary £31,542 - £33,257 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis. If the PhD has not yet been granted, the final accepted version of the thesis must have been submitted to the degree-granting university by the start date. Further Details A Job Description and Person Specification can be accessed at the bottom of this page. To apply for the vacancy, please click on the 'Apply Now' button below. If you have any queries about the application process, please contact Miss E Bertram, HR Manager, UCL Queen Square Institute of Neurology (email: IoN.HRAdmin@ucl.ac.uk). More information on the post or Alzheimer's Research UK UCL Drug Discovery Institute is available from Professor Paul Whiting (email: p.whiting@ucl.ac.uk). UCL Taking Action for Equality We will consider applications to work on a part-time, flexible and job share basis wherever possible. Closing Date 3 Nov 2020 Latest time for the submission of applications 23.59 Interview date TBC Our department holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality. This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff. Please use these links to find out more about UCL working life including the benefits we offer and UCL Terms and Conditions related to this job. Job Description and Person Specification Apply Now
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