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Position: Research Fellow
Institution: University College London
Department: Great Ormond Street Institute of Child Health - Developmental Biology and Cancer Programme
Location: London, United Kingdom
Duties: The post holder will join an expanding team of scientists at ICH as well as linking with collaborating teams at the Institute of Cancer Research, Mount Sinai Hospital (Toronto), and Sanford Burnham (USA), to use molecular, cellular and immunogenomic strategies to identify combinatorial therapeutic targets in clinically relevant mouse models of recurrent medulloblastoma. These will encompass CAR T-cell therapies and CRISPR-Cas9 functional strategies in immune competent humanised mouse models. The initial posting is for three years with the opportunity for extension
Requirements: The post holder will have previous experience of in vivo cancer-related pre-clinical trials, and experience in designing and implementing CRISPR-Cas9 functional technologies. A PhD in biological sciences and evidence of project completion through first author research publications in high impact peer reviewed journals is also essential
   
Text: Research Fellow, - Ref:1871902 Click here to go back to search results Apply Now UCL Department / Division Great Ormond Street Institute of Child Health Specific unit / Sub department Developmental Biology and Cancer Programme Location of position London Grade 7 Hours Full Time Salary (inclusive of London allowance) £35,965 per annum Duties and Responsibilities This is an exciting opportunity to join a newly established group based in the Developmental Biology and Cancer department at the UCL Great Ormond Street Institute of Child Health (UCL GOS ICH). Our research is focused on identifying and developing effective and safe therapeutic strategies for the treatment of recurrent medulloblastoma. Brain tumours are the leading cause of paediatric cancer-related deaths. Medulloblastomas are the most common malignant childhood brain tumour and essentially incurable at time of recurrence. The post holder will join an expanding team of scientists at ICH as well as linking with collaborating teams at the Institute of Cancer Research, Mount Sinai Hospital (Toronto), and Sanford Burnham (USA), to use molecular, cellular and immunogenomic strategies to identify combinatorial therapeutic targets in clinically relevant mouse models of recurrent medulloblastoma. These will encompass CAR T-cell therapies and CRISPR-Cas9 functional strategies in immune competent humanised mouse models. The initial posting is for three years with the opportunity for extension. This post is funded until 30 September 2023 in the first instance. Key Requirements The post holder will have previous experience of in vivo cancer-related pre-clinical trials, and experience in designing and implementing CRISPR-Cas9 functional technologies. A PhD in biological sciences and evidence of project completion through first author research publications in high impact peer reviewed journals is also essential. Further Details A job description and person specification can be accessed at the bottom of this page. To apply for the vacancy please click on the Apply Now button below. If you have any queries regarding the application process, please contact Khaled Islam at ich.hr@ucl.ac.uk quoting the job reference. For further details on the role, please contact Dr Laura Donovan at l.k.donovan@ucl.ac.uk. UCL Taking Action for Equality Closing Date 5 Oct 2020 Latest time for the submission of applications 23:59 Interview date TBC Our department holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality. This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff. Please use these links to find out more about UCL working life including the benefits we offer and UCL Terms and Conditions related to this job. Job Description Apply Now
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