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Position: Postdoctoral position - Epigenetic priming of apple rootstocks and their effects on scion development during drought stress
Institution: Institut national de la recherche agronomique
Location: Paris, France
Duties: The objective of the team is to investigate the potential use of epigenetics as a tool to improve perennial and clonally propagated plant production. Our plant model is apple (Malus domestica), which genome has been sequenced in 2017. Plants are continuously exposed to environmental perturbations. In the last few years, studies have revealed the importance of stress-induced chromatin changes, as well as modifications in DNA methylation levels, on gene transcription levels. This epigenetic-based plasticity could be a mechanism allowing clonal and perennial plant success
Requirements: Highly motivated candidates with a PhD degree and having a strong background in bioanalyses (data mining, interpretation, data aggregation…) and bioinformatics (genome assembly, …) are encouraged to apply. Previous experience with analyzing epigenomic and transcriptomic data is desirable. The candidates should also have good communication skills evidenced by scientific publications. Ability to work in a team environment is required
   
Text: Skip to main content INRAE EUROPE AND THE WORLD Reserved access en Get to know us open Get to know us Research professions open Research professions A quality work environment open A quality work environment Our advice open Our advice Career open Career Our identity open Our identity Our research topics open Our research topics Download leaflet INRAE leaflet Ambition and goals Key figures Agroecology Biodiversity Bioeconomy Climate change and risks Food, global health Society and regional strategies Scientific fields open Scientific fields Life sciences, earth sciences and environmental sciences Chemistry, material sciences Engineering science and instrumentation Digital sciences and modelling Humanities and social sciences The INRAE experience open The INRAE experience Develop your career open Develop your career Join a committed public sector employer open Join a committed public sector employer Dedicated and dynamic teams A quality workplace A good work-life balance Social support Your health at work Sports and cultural activities Start an apprenticeship Complete an internship Do your PhD at INRAE Receive career advice Develop your skills HR policy: an ongoing improvment process A disability-friendly employer HR Excellence in research Equality and diversity policy Sustainable development policy To pass an open competition open To pass an open competition What does a competitive examination involve? 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It is a community of 12,000 people with more than 200 research units and 42 experimental units located throughout France. The institute is among the world leaders in agricultural and food sciences, in plant and animal sciences, and is 11th in the world in ecology and environment. INRAE’s main goal is to be a key player in the transitions necessary to address major global challenges. In the face of the increase in population, climate change, scarcity of resources and decline in biodiversity, the institute develops solutions for multiperformance agriculture, high quality food and sustainable management of resources and ecosystems. Work environment, missions and activities A 18-month postdoc position is available at IRHS, Angers, France, starting from January 2021. Research will be performed in the VALEMA team (team leader JM Celton) at the “Institut de recherche en Horticulture et Semences” (https://www6.angers-nantes.inrae.fr/irhs/Recherche/VALorization-of-Epigenetic-Marks-in-plAnts) in collaboration with other teams from the institute, and with the Pland & Food Research Institute (New Zealand). The objective of the team is to investigate the potential use of epigenetics as a tool to improve perennial and clonally propagated plant production. Our plant model is apple (Malus domestica), which genome has been sequenced in 2017 (https://www.nature.com/articles/ng.3886). Plants are continuously exposed to environmental perturbations. In the last few years, studies have revealed the importance of stress-induced chromatin changes, as well as modifications in DNA methylation levels, on gene transcription levels. This epigenetic-based plasticity could be a mechanism allowing clonal and perennial plant success. In this project, using apple as a clonally propagated and perennial model plant we propose: (1) to investigate the capacity of the plant to adapt its transcriptomic and epigenomic response to drought stress (2) to investigate the memorization of the stress in the form of epigenomic modification (3) to study the transmission of the acquired epigenomic modifications to a new plant via clonal reproduction (grafting) (4) to investigate the rootstock-scion interaction by evaluating the potential capacity of a hydric stress-primed rootstock to influence the development of a naive grafted scion Missions: In relation with this these objectives, we are offering a 18-month postdoc position to perform epigenetic and transcriptomic analyses in order to identify key plant response factors involved in drought stress adaptation. You will: 1) implement a drought stress protocol on apple young seedlings and grafted plants 2) perform epigenetic (DMR identification) and transcriptomic (by RNA-seq) analyses 3) integrate ‘omic’ data in order to extract sensible biological responses 4) develop a methodological approach to assemble the genome of an apple rootstock Training and skills PhD Profile: Highly motivated candidates with a PhD degree and having a strong background in bioanalyses (data mining, interpretation, data aggregation…) and bioinformatics (genome assembly, …) are encouraged to apply. Previous experience with analyzing epigenomic and transcriptomic data is desirable. The candidates should also have good communication skills evidenced by scientific publications. Ability to work in a team environment is required. Important: The candidates should not have worked in France for more than 12 months during the past 3 years. Technical skills: Master in bioanalyses and bioinformatics or a related field with relevant expertise in the project topics. Experience with R tools are required as well INRAE's life quality By joining our teams, you benefit from: - 30 days of annual leave + 15 days "Reduction of Working Time" (for a full time); - parenting support: CESU childcare, leisure services; - skills development systems: training, career advise; - social support: advice and listening, social assistance and loans; - holiday and leisure services: holiday vouchers, accommodation at preferential rates; - sports and cultural activities; - collective catering. How to apply I send my CV and my motivation letter Offer reference Contract: Postdoctoral position Duration: 18 month Beginning: 01/01/2021 Remuneration: 2930 € gross/month Reference: OT-10332 Dealine: 31/10/2020 Centre Pays de la Loire UMR1345 IRHS Institut de Recherche en Horticulture et Semences 49071 BEAUCOUZE Contact Jean-Marc CELTON jean-marc.celton@inrae.fr Sandrine BALZERGUE: sandrine.balzergue@inrae.fr Share on Facebook Share on Twitter Share on Linkedin close print share_by_mail share_by_link link_copied scroll_to_top Follow us Headquarters: 147 rue de l'Université 75338 Paris Cedex 07 - tél. : +33(0)1 42 75 90 00 Copyright - ©INRAE Credits ToU GTCP Accessibility: not compliant Contact Get to know us Research professions Research professions Scientific fields Scientific fields Life sciences, earth sciences and environmental sciences Chemistry, material sciences Engineering science and instrumentation Digital sciences and modelling Humanities and social sciences A quality work environment A quality work environment The INRAE experience The INRAE experience Dedicated and dynamic teams A quality workplace A good work-life balance Social support Your health at work Sports and cultural activities Develop your career Develop your career Start an apprenticeship Complete an internship Do your PhD at INRAE Receive career advice Develop your skills Join a committed public sector employer Join a committed public sector employer HR policy: an ongoing improvment process A disability-friendly employer HR Excellence in research Equality and diversity policy Sustainable development policy Our advice Our advice To pass an open competition To pass an open competition What does a competitive examination involve? The step-by-step approach to getting ready for a competitive examination Breaking down misconceptions about competitive examinations Understanding our public service corps according to your profile The keys to success at an INRAE competitive examination Career Career Welcome to INRAE Welcome to INRAE New employee handbook Paid leave and working hours Rights, obligations and code of conduct Support for foreign staff Building your professional career Building your professional career You passed an INRAE competitive exam You are on temporary assigment Receive career advice Develop your skills Réaliser une mobilité interne Your remuneration Your remuneration Remuneration of tenured staff Remuneration of contractuel staff Get to know us Get to know us Our identity Our identity INRAE leaflet Ambition and goals Key figures Our research topics Our research topics Agroecology Biodiversity Bioeconomy Climate change and risks Food, global health Society and regional strategies Research professions Research professions Scientific fields Scientific fields Life sciences, earth sciences and environmental sciences Chemistry, material sciences Engineering science and instrumentation Digital sciences and modelling Humanities and social sciences A quality work environment A quality work environment The INRAE experience The INRAE experience Dedicated and dynamic teams A quality workplace A good work-life balance Social support Your health at work Sports and cultural activities Develop your career Develop your career Start an apprenticeship Complete an internship Do your PhD at INRAE Receive career advice Develop your skills Join a committed public sector employer Join a committed public sector employer HR policy: an ongoing improvment process A disability-friendly employer HR Excellence in research Equality and diversity policy Sustainable development policy Our advice Our advice To pass an open competition To pass an open competition What does a competitive examination involve? The step-by-step approach to getting ready for a competitive examination Breaking down misconceptions about competitive examinations Understanding our public service corps according to your profile The keys to success at an INRAE competitive examination Career Career Welcome to INRAE Welcome to INRAE New employee handbook Paid leave and working hours Rights, obligations and code of conduct Support for foreign staff Building your professional career Building your professional career You passed an INRAE competitive exam You are on temporary assigment Receive career advice Develop your skills Your remuneration Your remuneration Remuneration of tenured staff Remuneration of contractuel staff INRAE EUROPE AND THE WORLD
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