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Position: Postdoctoral Position in Development of Cancer-targeted Nanoparticles Activating Immune System
Institution: Universität Basel
Location: Basel, Switzerland
Duties: The overall aim of this project is the development of cancer-targeted nanoparticles activating immune system by thorough characterization of their physicochemical properties and cell interactions in order to better understand their mode of action and facilitate clinical application of the unique drug platform. A particularly important part of the project will intend to evaluate various molecular properties, such as architecture, size distribution, polydistersity (PDI), surface charge in different formulation conditions and environment (e.g. buffer, pH, concentration) both of the; carriers and when they are loaded with the payload. In addition, encapsulation efficiency of the payload and the interaction with cells represent key elements for the overall efficiency of the cancertargeted nanoparticles activating immune system
Requirements: you will ideally have a PhD in chemistry, biochemistry or biophysics; experience in physical-chemistry methods to characterize colloidal nanosystems is a must; knowledge of molecular biology techniques (e.g. PCR, DNA purification); experience in nanoscience-based drug delivery systems is desirable; high records of publications in internationally refereed scientific journals; proficiency in English; German is an advantage
   
Text: Universität Basel: Postdoctoral Position Postdoctoral Position in Development of Cancer-targeted Nanoparticles Activating Immune System We invite candidates to submit applications for a PostDoc position in the nanoscience-oriented physical chemistry group of Professor C. Palivan, Department of Chemistry, at the University of Basel, Switzerland. The position is for one year, with possible prolongation up to two years. Your position The overall aim of this project is the development of cancer-targeted nanoparticles activating immune system by thorough characterization of their physicochemical properties and cell interactions in order to better understand their mode of action and facilitate clinical application of the unique drug platform. A particularly important part of the project will intend to evaluate various molecular properties, such as architecture, size distribution, polydistersity (PDI), surface charge in different formulation conditions and environment (e.g. buffer, pH, concentration) both of the carriers and when they are loaded with the payload. In addition, encapsulation efficiency of the payload and the interaction with cells represent key elements for the overall efficiency of the cancertargeted nanoparticles activating immune system. This is an interdisciplinary project with industry partners from which you will gain valuable experience in the domain of nanoscience, physical chemistry, and novel drug delivery approaches. Your role will be to insert the payload and characterize the cancer-targeted nanoparticles activating immune system in various conditions to optimize their efficiency, control their cell interaction and understand their mode of action to support clinical application. More information on the topics of the group in which you will be working can be found at http://www.chemie1.unibas.ch/~palivan/ or at https://chemie.unibas.ch/de/forschung/nanomaterialien/ Your profile you will ideally have a PhD in chemistry, biochemistry or biophysics; experience in physical-chemistry methods to characterize colloidal nanosystems is a must; knowledge of molecular biology techniques (e.g. PCR, DNA purification); experience in nanoscience-based drug delivery systems is desirable; high records of publications in internationally refereed scientific journals proficiency in English; German is an advantage. Application / Contact For further information, please contact Prof. Dr. Cornelia Palivan, (Cornelia.Palivan@unibas.ch, phone: 41.61.2673839). Interested candidates will send, by 10.03.2020: i. letter of motivation, ii. curriculum vitae, iii. names and contact details for two referees. www.unibas.ch
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