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Position: Research Fellow
Institution: University College London
Department: UCL Queen Square Institute of Neurology - UK Dementia Research Institute (UK DRI) @ UCL
Location: London, United Kingdom
Duties: The successful applicant will apply novel, sophisticated in vitro, ex vivo and in vivo approaches to track and examine the role of tau in disease cases in human and mouse models and cell model systems. In addition, the candidate will explore the mechanisms by which tau aggregates spread through the brain, and ways to prevent spread, to generate an understanding of how best to create disease-relevant assays. The post is available immediately and is funded by the UK DRI at UCL for a period of two years in the first instance
Requirements: The successful candidate will hold, or be close to obtaining, a PhD in biological science. Experience in molecular/cellular neurobiology, especially of the pathogenic processes underlying Alzheimer's and Frontotemporal dementia linked to tau, developing and implementing high resolution, single cell or molecule techniques for assessing tau and related proteins in human, mouse and/or cell samples, and working with human derived samples is essential. A proven level of technical skill in assessing tau or other disease associated proteins, and abilities in assessment of ultra low levels of proteins, immunohistochemistry/immunofluorescence, biochemical and molecular biology techniques, excellent oral and written communication and inter-personal skills, and a commitment to working ethically, legally and with integrity are also required
   
Text: Research Fellow, - Ref:1857706 Click here to go back to search results Apply Now UCL Department / Division UCL Queen Square Institute of Neurology Specific unit / Sub department UK Dementia Research Institute (UK DRI) @ UCL Location of position London Grade 7 Hours Full Time Salary (inclusive of London allowance) £35,965 - £43,470 per annum Duties and Responsibilities Dementia is the greatest health challenge of our century. The UK Dementia Research Institute ( https://ukdri.ac.uk/ - UK DRI) is the biggest initiative supporting research to fill this gap. Research from UK DRI at UCL ( https://www.ucl.ac.uk/uk-dementia-research-institute/ ) covers the journey from the patient to the laboratory and back to the patient with improved diagnosis, biomarkers and candidate therapies put to the test. The Duff lab is looking for a highly-motivated, experienced and self-driven individual to work on an exciting project that aims to examine the mechanisms underlying tau pathogenesis in Alzheimer's and FTD. The successful applicant will apply novel, sophisticated in vitro, ex vivo and in vivo approaches to track and examine the role of tau in disease cases in human and mouse models and cell model systems. In addition, the candidate will explore the mechanisms by which tau aggregates spread through the brain, and ways to prevent spread, to generate an understanding of how best to create disease-relevant assays. The post is available immediately and is funded by the UK DRI at UCL for a period of two years in the first instance. Key Requirements The successful candidate will hold, or be close to obtaining, a PhD in biological science. Experience in molecular/cellular neurobiology, especially of the pathogenic processes underlying Alzheimer's and Frontotemporal dementia linked to tau, developing and implementing high resolution, single cell or molecule techniques for assessing tau and related proteins in human, mouse and/or cell samples, and working with human derived samples is essential. A proven level of technical skill in assessing tau or other disease associated proteins, and abilities in assessment of ultra low levels of proteins, immunohistochemistry/immunofluorescence, biochemical and molecular biology techniques, excellent oral and written communication and inter-personal skills, and a commitment to working ethically, legally and with integrity are also required. Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary £31,965 - £33,194 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.If the PhD has not yet been granted, the final accepted version of the thesis must have been submitted to the degree-granting university by the start date. Further Details A Job Description and Person Specification can be accessed at the bottom of this page. To apply for the vacancy, please click on the 'Apply Now' button below. If you have any queries regarding the application process, please contact Miss E Bertram, HR Manager, UCL Queen Square Institute of Neurology, 23 Queen Square, London, WC1N 3BG (email: ion.hradmin@ucl.ac.uk). For informal enquiries about the role, please contact Karen Duff (email: k.duff@ucl.ac.uk). UCL Taking Action for Equality We will consider applications to work on a part-time, flexible and job share basis wherever possible. Closing Date 26 Jan 2020 Latest time for the submission of applications 23.59 Interview date TBC Our department holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality. This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff. Please use these links to find out more about UCL working life including the benefits we offer and UCL Terms and Conditions related to this job. Job Description and Person Specification Apply Now
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