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Position: Research Fellow/Senior Research Fellow in Bioinformatics/Computational Biology
Institution: University College London
Department: Research Department of Structural and Molecular Biology
Location: London, United Kingdom
Duties: CATH is an internationally renowned resource providing information on sequence-structure-function relationships for over a hundred million proteins. We are recruiting a postdoctoral researcher at either Grade 7 or 8, depending on experience. This post will develop new computational algorithms and protocols exploiting machine learning for better functional classification of domains in CATH. This is a collaborative project with PDBe, UniProt, SWISS-MODEL, Rosetta, ModBase which will improve the functional classification of CATH domains to provide templates for improved protein structure prediction and to improve functional site prediction. The Orengo group exploits CATH data in a range of collaborations with experimental groups researching the impacts of genetic variations (eg cancer studies, protein design to engineer enzymes for improved plastic degradation) and the postdoc would also be able to contribute to these projects. Expertise in website design and development would also be an advantage to present the functional classification data intuitively to the large community exploiting this CATH data
Requirements: You should hold a PhD in a relevant field (computer science, bioinformatics or computational biology) or be about to submit a thesis. Advanced programming skills and experience of Perl or Python, databases and SQL, Linux or other unix-like operating systems are all essential for the role. Previous experience in bioinformatics research is desirable, especially in protein structure-function analysis and prediction
   
Text: Research Fellow/ Senior Research Fellow in Bioinformatics/Computational Biology, - Ref:1822760 Click here to go back to search results Apply Now UCL Department / Division Research Department of Structural and Molecular Biology Location of position London Grades 7-8 Hours Full Time Salary (inclusive of London allowance) £35,965 - £43,470 Grade 7 & £44,674 - £52,701 Grade 8 Duties and Responsibilities Exploiting evolutionary data to identify protein functional families for modelling protein structures and predicting their functions and functional sites. CATH is an internationally renowned resource providing information on sequence-structure-function relationships for over a hundred million proteins. We are recruiting a postdoctoral researcher at either Grade 7 or 8, depending on experience. This post will develop new computational algorithms and protocols exploiting machine learning for better functional classification of domains in CATH. This is a collaborative project with PDBe, UniProt, SWISS-MODEL, Rosetta, ModBase which will improve the functional classification of CATH domains to provide templates for improved protein structure prediction and to improve functional site prediction. The Orengo group exploits CATH data in a range of collaborations with experimental groups researching the impacts of genetic variations (eg cancer studies, protein design to engineer enzymes for improved plastic degradation) and the postdoc would also be able to contribute to these projects. Expertise in website design and development would also be an advantage to present the functional classification data intuitively to the large community exploiting this CATH data. This post is funded for 3 years in the first instance and will be based in the lab of Professor Christine Orengo at UCL. The project is in collaboration with the Protein Databank at EBI. Key Requirements To apply at Grade 7 and above, you should hold a PhD in a relevant field (computer science, bioinformatics or computational biology) or be about to submit a thesis. Advanced programming skills and experience of Perl or Python, databases and SQL, Linux or other unix-like operating systems are all essential for the role. Previous experience in bioinformatics research is desirable, especially in protein structure-function analysis and prediction. If the PhD is yet to be awarded, initial appointment will be at research assistant Grade 6B (salary £31,479-£33,194 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis. In addition to the above, to be appointed at Grade 8 as Senior Research Fellow the successful candidate will have an independent research reputation, with evidence of national recognition of achievement within the appropriate subject area. Evidence of completed research, which has been published, as well as a suitable publication record, and evidence of knowledge transfer/exchange activities is also essential. Further Details A job description and person specification can be accessed at the bottom of this page. Please read these carefully before applying. To apply for the vacancy please click on the 'Apply Now' button below. For informal queries on the role, please contact Prof Christine Orengo c.orengo@ucl.ac.uk . For queries regarding the application process, please contact the Biosciences Staffing team biosciences.staffing@ucl.ac.uk . We particularly welcome female applicants and those from an ethnic minority, as they are under-represented within UCL at this level. UCL Taking Action for Equality We will consider applications to work on a part-time, flexible and job share basis wherever possible. Closing Date 20 Oct 2019 Latest time for the submission of applications 23:59 Interview date tbc Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality. This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff. Please use these links to find out more about UCL working life including the benefits we offer and UCL Terms and Conditions related to this job. Job description & Person Specification Apply Now
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