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Position: Research Fellow
Institution: University College London
Department: UCL Institute of Ophthalmology
Location: London, United Kingdom
Duties: The postholder will use standard molecular biology techniques including: plasmid preparation, DNA extraction, PCR genotyping, sequencing, nucleic acid extraction and purification etc. He/she will also use Immunocytochemistry, standard biochemistry, RNA work, RT-PCR, qPCR, Luciferase assays, and Minigene analysis
Requirements: A good understanding of at least one of the following is essential: molecular genetics, gene transcription, splicing and translation/expression, inherited retinal dystrophies, cell biology; Candidates should be bright, independent and highly motivated, but they must also be willing and able to work effectively as part of a team. They should be willing to contribute to manuscripts for publication, present findings at lab meetings, departmental meetings and national/international conferences and to supervise junior members of staff and students
   
Text: Research Fellow, - Ref:1817309 Click here to go back to search results Apply Now UCL Department / Division UCL Institute of Ophthalmology Location of position London Grade 7 Hours Full Time Salary (inclusive of London allowance) £35,328 - £42,701 per annum Duties and Responsibilities There is a vacancy for a Research Fellow to join a small research team led by Dr Gavin Arno and Dr Omar Mahroo, to investigate the molecular mechanisms of novel candidate causes of inherited retinal dystrophy (IRD). The position is funded by the Wellcome Trust (Grant 206619/Z/17/Z), and relates to a wider project aimed at understanding retinal function through non-invasive electrophysiological recordings in patients with IRD. The funding is for 2 years in the first instance. The research group is part of the wider collaborative team headed by Professor Andrew R Webster and is part of the UCL Institute of Ophthalmology. The postholder will use standard molecular biology techniques including: plasmid preparation, DNA extraction, PCR genotyping, sequencing, nucleic acid extraction and purification etc. He/she will also use Immunocytochemistry, standard biochemistry, RNA work, RT-PCR, qPCR, Luciferase assays, and Minigene analysis. The Research Fellow will work closely with the other members of the group, but will be responsible for the day to day management of their own time and research. The project will require a wide range of complementary, contemporary molecular and cell biology techniques. In particular, the research will use RNA and transcript analysis from patient cells and tissue, qPCR, cloning, mini-gene and luciferase reporter assays in the characterisation of effect of novel non-coding variants. Experience in some or all of these techniques is essential. In addition, there will be scope to gain experience in single molecule long-read sequencing sample and library preparation for sequencing runs and targeting of this technology using CRISPR guides. Key Requirements A good understanding of at least one of the following is essential: molecular genetics, gene transcription, splicing and translation/expression, inherited retinal dystrophies, cell biology. Candidates should be bright, independent and highly motivated, but they must also be willing and able to work effectively as part of a team. They should be willing to contribute to manuscripts for publication, present findings at lab meetings, departmental meetings and national/international conferences and to supervise junior members of staff and students. Further Details A job description and person specification can be accessed at the bottom of this page. To apply for the vacancy please click on the 'Apply Now' button below. Informal enquiries about the post may be made to Dr Gavin Arno (email: g.arno@ucl.ac.uk ). If you have any enquiries regarding the application process please email: hr.ioo@ucl.ac.uk . UCL Taking Action for Equality We will consider applications to work on a part-time, flexible and job share basis wherever possible. Closing Date 17 Jul 2019 Latest time for the submission of applications 23:59 Interview date TBC Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality. This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff. Please use these links to find out more about UCL working life including the benefits we offer and UCL Terms and Conditions related to this job. Job Description and Person Specification Apply Now
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