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Position: Research Fellow
Institution: University College London
Department: Great Ormond Street Institute of Child Health
Location: London, United Kingdom
Duties: We have a unique opportunity for a talented post-doctoral fellow to participate in a cutting edge translational research project sponsored by the F. Hoffmann-La Roche Ltd. Post- Doctoral Fellowship programme (RPF) and hosted by the Dubowitz Neuromuscular Centre (DNC) at the UCL Great Ormond Street Institute of Child Health. The goal of the project is to further validate the role of lncRNA function in muscle biology and to explore its relevance as a potentially new therapeutic approach for Duchenne muscular dystrophy. The aim is to assess therapeutic efficacy in an animal model of the disease. This research project combines molecular biology techniques with histopathology, muscle function assessments, and adeno associated viral vector gene therapy
Requirements: Applicants must have a PhD in molecular Biology or other relevant subject. Applicants must be in their first 5 years after obtaining a PhD degree as required from the funder. A strong background in molecular biology, especially cloning and expression vector design, is absolutely required. The ideal candidate should also have experience with mammalian cell culture, reporter assays, and be willing to perform experiments involving mice. Excellent verbal and written communication skills are required to communicate research findings in peer reviewed journals and scientific presentations. The post-holder will work closely with existing staff at the Dubowitz Neuromuscular Centre but must have the ability to work independently
   
Text: Research Fellow, - Ref:1809740 Click here to go back to search results Apply Now UCL Department / Division Great Ormond Street Institute of Child Health Location of position London Grade 7 Hours Full Time Salary (inclusive of London allowance) £35,328 - £42,701 per annum Duties and Responsibilities We have a unique opportunity for a talented post-doctoral fellow to participate in a cutting edge translational research project sponsored by the F. Hoffmann-La Roche Ltd. Post- Doctoral Fellowship programme (RPF) and hosted by the Dubowitz Neuromuscular Centre (DNC) at the UCL Great Ormond Street Institute of Child Health. The goal of the project is to further validate the role of lncRNA function in muscle biology and to explore its relevance as a potentially new therapeutic approach for Duchenne muscular dystrophy. The aim is to assess therapeutic efficacy in an animal model of the disease. This research project combines molecular biology techniques with histopathology, muscle function assessments, and adeno associated viral vector gene therapy. The successful candidate will be supervised and mentored by Dr. Montanaro and Prof. Muntoni at the DNC as well as the project leader in Roches Rare Disease organisation. The RPF Fellow will have the opportunity to attend the yearly international RPF symposium hosted by one of Roches global pRED research sites to enable critical scientific exchange and interaction with other RPFs, Roche employees and academic mentors. The DNC is one of the worlds top translational research centres for the study and treatment of paediatric neuromuscular disorders. The DNC has its own programme to support career progression of post-doctoral fellows and students, in particular relating to grant and fellowship applications. The successful candidate is expected to take advantage of this internal training programme. The post is available for one year in the first instance. Key Requirements Applicants must have a PhD in molecular Biology or other relevant subject. Applicants must be in their first 5 years after obtaining a PhD degree as required from the funder. A strong background in molecular biology, especially cloning and expression vector design, is absolutely required. The ideal candidate should also have experience with mammalian cell culture, reporter assays, and be willing to perform experiments involving mice. Excellent verbal and written communication skills are required to communicate research findings in peer reviewed journals and scientific presentations. The post-holder will work closely with existing staff at the Dubowitz Neuromuscular Centre but must have the ability to work independently. Further Details A job description and person specification can be accessed at the bottom of this page. To apply for the vacancy please click on the Apply Now button below. If you have any queries regarding the application process, please contact Madhur Sharma on ich.hr@ucl.ac.uk quoting job reference number. UCL Taking Action for Equality Closing Date 7 Jul 2019 Our department holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality. This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff. Please use these links to find out more about UCL working life including the benefits we offer and UCL Terms and Conditions related to this job. Job Description and Person Specification Apply Now
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