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Position: Postdoс - Bioinformatics
Institution: Universität Basel
Department: Biomedicine
Location: Basel, Switzerland
Duties: We seek a highly motivated postdoc with a strong background in bioinformatic analysis of genome-wide datasets. Our lab is interested in understanding molecular pathways involved in immune regulation. We focus on miRNAs and miRNA-regulated genetic networks in T cells. We combine genetic mouse models with various -omics approaches and apply the latest genome engineering tools to dissect molecular pathways in mouse and human cells. You will help to plan future experiments, analyze existing datasets generated in the lab, integrate datasets from public data repositories and contribute to interpretation of the results (e.g. RNA-Seq, HITS-CLIP, genome-wide CRISPR screening, metabolomics, proteomics, targeted genome engineering experiments)
Requirements: A PhD degree in a quantitative field (bioinformatics, statistics, physics or mathematics) with a strong interest in the analysis of biological systems. Some basic knowledge of immunology. At least two-years hands-on experience with next generation sequence data analysis. Good statistical and R/Bioconductor programming skills are essential
   
Text: Postdoctoral Position: Bioinformatics 100% The Molecular Immune Regulation group at the Department of Biomedicine of the University Hospital Basel in Switzerland is seeking a highly motivated postdoc with a strong background in bioinformatic analysis of genome-wide datasets. Our lab is interested in understanding molecular pathways involved in immune regulation. We focus on miRNAs and miRNA-regulated genetic networks in T cells. We combine genetic mouse models with various -omics approaches and apply the latest genome engineering tools to dissect molecular pathways in mouse and human cells (Baumjohann et al., Nat Imm, 2013; Kornete et al, J Imm, 2018). In addition, we develop new concepts for genome engineering-based cell therapy. Your position You help to plan future experiments, analyze existing datasets generated in the lab, integrate datasets from public data repositories and contribute to interpretation of the results (e.g. RNA-Seq, HITS-CLIP, genome-wide CRISPR screening, metabolomics, proteomics, targeted genome engineering experiments) Beside your assistance to other lab members, you are highly encouraged to develop and lead your own project You interact closely with the bioinformatics core facility and other embedded bioinformaticians at the institute Your profile The successful candidate is expected to have: A PhD degree in a quantitative field (bioinformatics, statistics, physics or mathematics) with a strong interest in the analysis of biological systems Some basic knowledge of immunology At least two-years hands-on experience with next generation sequence data analysis Good statistical and R/Bioconductor programming skills are essential Excellent communication, and teamwork skills We offer you Cutting-edge, challenging science in a stimulating and well-funded (SNSF, NIH, ERC) research group, with state-of-the art equipment. Flexible working hours Support and interactions with the local bioinformatics community at the DBM, and nationally through the Swiss Institute of Bioinformatics (https://www.sib.swiss). Integration to a lively immunology community with regular seminars by renowned speakers and an annual retreat Competitive salary according to guidelines of the University of Basel/Swiss National Science Foundation Application / Contact Please send a letter of motivation, CV and contact information including e-mail address of three references to: Nicole Salvisberg nicole.salvisberg@unibas.ch, assistant to Prof. Lukas Jeker, Experimental Transplantation Immunology & Nephrology. Please include "Bioinformatics Postdoc" in the subject line. www.unibas.ch
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