Visit www.acad.jobs with all Jobs for Academics!
                    
Position: Research Fellow - Biomedical Molecular Dynamics for Drug Discovery
Institution: University College London
Department: Chemistry
Location: London, United Kingdom
Duties: You will join a very active inter-disciplinary group in the Centre for Computational Science, working on projects in fields ranging from condensed matter physics and chemistry to life sciences and medicine. This post will involve the development of molecular models to support computer-based drug discovery and to investigate the biophysical and biochemical origins of drug resistance in pathologies such as HIV, cancer, and antimicrobial resistance, using established molecular dynamics codes such as NAMD and OpenMM. A key element of the approach is the development and use of automated workflows to assist in the rapid, accurate, precise and reproducible determination of binding affinities running on a range of ultra-high-end supercomputers
Requirements: A PhD degree (or near to being awarded a PhD) in biomolecular dynamics as used to perform free energy and related calculations of ligand-protein binding is essential, as is extensive experience with high performance computing. The postholder must also have experience of using common molecular dynamics packages including at least two of NAMD, AMBER, GROMACS and OpenMM. An excellent and consistent publication track record is also essential
   
Text: Research Fellow in Biomedical Molecular Dynamics for Drug Discovery, - Ref:1796578 Click here to go back to search results Apply Now UCL Department / Division Chemistry Location of position London Grade 7 Hours Full Time Salary (inclusive of London allowance) ?35,328 - ?42,701 per annum. Duties and Responsibilities Applications are invited for a Research Fellow to work with Professor Peter Coveney in the Department of Chemistry at University College London. The successful candidate will join a very active inter-disciplinary group in the Centre for Computational Science, working on projects in fields ranging from condensed matter physics and chemistry to life sciences and medicine. This post will involve the development of molecular models to support computer-based drug discovery and to investigate the biophysical and biochemical origins of drug resistance in pathologies such as HIV, cancer, and antimicrobial resistance, using established molecular dynamics codes such as NAMD and OpenMM. A key element of the approach is the development and use of automated workflows to assist in the rapid, accurate, precise and reproducible determination of binding affinities running on a range of ultra-high-end supercomputers, including Summit, number one in the Top500 list of supercomputers worldwide. The postholder will work closely with a large number of international projects across Europe and USA, and with collaborating industrial (pharma/biotech) and public sector partners who have an interest in exploiting our approaches in industry and healthcare. The post is funded by the European Commission and is available from 1 April 2019, for a period of 24 months initially. Key Requirements A PhD degree (or near to being awarded a PhD) in biomolecular dynamics as used to perform free energy and related calculations of ligand-protein binding is essential, as is extensive experience with high performance computing. The postholder must also have experience of using common molecular dynamics packages including at least two of NAMD, AMBER, GROMACS and OpenMM. An excellent and consistent publication track record is also essential. Please note, appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Research Assistant Grade 6B (salary ?30,922 to ?32,607 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis. Further Details A Job Description and Person Specification can be accessed at the bottom of this page. Please include a publication list along with CV. To apply for the vacancy please click on the 'Apply Now' button below. Informal enquiries should be addressed to Prof Peter Coveney ( p.v.coveney@ucl.ac.uk ). Any queries on the application process can be directed to Judith James ? j.k.james@ucl.ac.uk . We particularly welcome female applicants and those from an ethnic minority, as they are under-represented within UCL at this level. Closing Date 10 Apr 2019 Latest time for the submission of applications 23:59 Interview date TBC Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality. This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff. Please use these links to find out more about UCL working life including the benefits we offer and UCL Terms and Conditions related to this job. Job Description and Person Specification Apply Now
Please click here, if the Job didn't load correctly.







Please wait. You are being redirected to the Job in 3 seconds.